PA550647
Cullin 4B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550647-Each-of-1 | In Stock | ₹ 44,705.10 |
PA550647 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Cullin 4B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CUL4B
Gene Alias
2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8450
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
2.7 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q13620
Gene Symbols
CUL4B
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human cullin 4B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total Cullin 4B protein
- Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
- The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
- CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
- Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
- Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
- Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
- Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
- Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.
Compare Similar Items
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Antigen: Cullin 4B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUL4B
Gene Alias: 2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8450
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 2.7 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q13620
Gene Symbols: CUL4B
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cullin 4B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Cullin 4B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUL4B
Gene Alias:
2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8450
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
2.7 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q13620
Gene Symbols:
CUL4B
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human cullin 4B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DSC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DSC1
Gene Alias: 1110020A10Rik; AI507491; Cadherin family member 1; CDHF1; desmocollin 1; Desmocollin1; desmocollin-1; Desmosomal glycoprotein 2/3; DG2/DG3; DSC1; Dsc1a; Dsc1b
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1823
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 2.8 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q08554
Gene Symbols: DSC1
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human desmocollin 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DSC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DSC1
Gene Alias:
1110020A10Rik; AI507491; Cadherin family member 1; CDHF1; desmocollin 1; Desmocollin1; desmocollin-1; Desmosomal glycoprotein 2/3; DG2/DG3; DSC1; Dsc1a; Dsc1b
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1823
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
2.8 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q08554
Gene Symbols:
DSC1
Immunogen:
Synthetic peptide corresponding to residues near the C terminal of human desmocollin 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DIRAS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Diras1
Gene Alias: DIRAS family GTP binding RAS like 1; DIRAS family GTPase 1; DIRAS family, GTP-binding RAS-like 1; DIRAS1; Di-Ras1; Distinct subgroup of the Ras family member 1; GBTS1; GTP-binding protein Di-Ras1; ras-related inhibitor of cell growth; RIG; small GTP-binding tumor suppressor 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 148252
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 2.4 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O95057
Gene Symbols: Diras1
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human DIRAS family, GTP-binding RAS-like 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DIRAS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Diras1
Gene Alias:
DIRAS family GTP binding RAS like 1; DIRAS family GTPase 1; DIRAS family, GTP-binding RAS-like 1; DIRAS1; Di-Ras1; Distinct subgroup of the Ras family member 1; GBTS1; GTP-binding protein Di-Ras1; ras-related inhibitor of cell growth; RIG; small GTP-binding tumor suppressor 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
148252
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
2.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O95057
Gene Symbols:
Diras1
Immunogen:
Synthetic peptide corresponding to residues near the C terminal of human DIRAS family, GTP-binding RAS-like 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: AGO1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ago1
Gene Alias: AGO1; argonaute 1; argonaute 1, RISC catalytic component; argonaute RISC catalytic component 1; argonaute RISC catalytic subunit 1; argonaute1; EIF2C; eIF2C 1; eIF-2C 1; EIF2C1; Eukaryotic translation initiation factor 2C 1; eukaryotic translation initiation factor 2C, 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; mAgo1; Piwi/Argonaute family protein meIF2C1; Protein argonaute-1; putative RNA-binding protein Q99; Q99
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 236511, 26523
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 2.6 mg/mL
Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q8CJG1, Q9UL18
Gene Symbols: Ago1
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human argonaute RISC catalytic component 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
AGO1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ago1
Gene Alias:
AGO1; argonaute 1; argonaute 1, RISC catalytic component; argonaute RISC catalytic component 1; argonaute RISC catalytic subunit 1; argonaute1; EIF2C; eIF2C 1; eIF-2C 1; EIF2C1; Eukaryotic translation initiation factor 2C 1; eukaryotic translation initiation factor 2C, 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; mAgo1; Piwi/Argonaute family protein meIF2C1; Protein argonaute-1; putative RNA-binding protein Q99; Q99
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
236511, 26523
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
2.6 mg/mL
Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q8CJG1, Q9UL18
Gene Symbols:
Ago1
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human argonaute RISC catalytic component 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG