PA550746

RRAS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA550746-Each-of-1 In Stock ₹ 45,218.46

PA550746 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

RRAS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RRAS

Gene Alias

AI573426; Harvey rat sarcoma oncogene, subgroup R; Harvey rat sarcoma virus oncogene, subgroup R; oncogene RRAS; p23; ras family small GTP binding protein R-Ras; ras-related protein R-Ras; Ras-related protein R-RAS (P23); related RAS viral (r-ras) oncogene homolog; RRAS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20130, 361568, 6237

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.9 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

D3Z8L7, P10301, P10833

Gene Symbols

RRAS

Immunogen

Synthetic peptide corresponding to residues near the N terminal of human related RAS viral (r-ras) oncogene homolog

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total RRA S protein
  • The Ras superfamily of small GTPases includes the Ras, Rho, Arf, Rab, and Ran families
  • Ras-regulated signal pathways control such as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration
  • These GTPases function as molecular switches that control eukaryotic cell function by cycling between two interconvertible forms, a GDP-bound inactive form and a GTP-bound active form
  • The binding of GTP leads to a conformational change in the downstream effector-binding domain of the G-protein
  • The small GTPases are monomeric G-proteins with molecular masses over the range 20-30 kDa
  • Ras is attached to the cell membrane by prenylation
  • Mutations in the Ras family of proto-oncogenes (comprising H-Ras, N-Ras and K-Ras) are very common, being found in 20% to 30% of all human tumours
  • The frequency of RAS mutations is among the highest for any gene in human cancer
  • K-ras mutations occur frequently in non-small-cell lung, colorectal, and pancreatic carcinomas; H-ras mutations are common in bladder, kidney, and thyroid carcinomas; N-ras mutations are found in melanoma, hepatocellular carcinoma, and hematologic malignancies.

Compare Similar Items

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Thermo Scientific

PA550746

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Antigen:
RRAS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RRAS

Gene Alias:
AI573426; Harvey rat sarcoma oncogene, subgroup R; Harvey rat sarcoma virus oncogene, subgroup R; oncogene RRAS; p23; ras family small GTP binding protein R-Ras; ras-related protein R-Ras; Ras-related protein R-RAS (P23); related RAS viral (r-ras) oncogene homolog; RRAS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20130, 361568, 6237

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.9 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
D3Z8L7, P10301, P10833

Gene Symbols:
RRAS

Immunogen:
Synthetic peptide corresponding to residues near the N terminal of human related RAS viral (r-ras) oncogene homolog

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA550750

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Antigen:
CWC27

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cwc27

Gene Alias:
3110009E13Rik; Antigen NY-CO-10; CWC27; CWC27 spliceosome associated protein homolog; CWC27 spliceosome-associated protein homolog; CWC27 spliceosome-associated protein homolog (S. cerevisiae); NY-CO-10; peptidyl-prolyl cis-trans isomerase CWC27 homolog; peptidyl-prolyl cis-trans isomerase SDCCAG10; PPIase CWC27; PPIase SDCCAG10; Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog; SDCCAG10; SDCCAG-10; Serologically defined colon cancer antigen 10; Spliceosome-associated protein CWC27 homolog; UNQ438/PRO871

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10283

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q6UX04

Gene Symbols:
Cwc27

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human CWC27 spliceosome-associated protein homolog (S. cerevisiae)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550752

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Antigen:
SEPN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SELENON

Gene Alias:
1110019I12Rik; AI414492; cb686; CFTD; FLJ24021; MDRS1; RSMD1; RSS; selenon; Selenoprotein N; selenoprotein N, 1; SELN; SePN; sepn1; wu:fb06g01; wu:fb73d02; wu:fv41b08; zgc:101091

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57190

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9NZV5

Gene Symbols:
SELENON

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human selenoprotein N, 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550753

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Antigen:
SEMA7A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEMA7A

Gene Alias:
2900057C09Rik; CD108; CDw108; H-Sema K1; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; MGC126692; MGC126696; M-Sema-L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A, GPI membrane anchor; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; semaphorin-7A; Semaphorin-K1; semaphorin-L; Semk1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20361, 8482

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.9 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O75326, Q9QUR8

Gene Symbols:
SEMA7A

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG