PA551045
CDCA2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA551045-Each-of-1 | In Stock | ₹ 44,705.10 |
PA551045 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CDCA2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDCA2
Gene Alias
2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
157313
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q69YH5
Gene Symbols
CDCA2
Immunogen
Synthesized peptide derived from the Internal region of human Repo-Man.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- CDCA2 Polyclonal Antibody detects endogenous levels of CDCA2 protein
- Cell division cycle associated 2 (CDCA2, Repo-Man) is a cell-cycle protein that recruits protein phosphatase 1 (PP1) to mitotic chromatin at anaphase onset, which is essential for cell proliferation
- Carboxy-terminal phosphorylation of CDCA2 at Ser893 by Aurora B inhibits the protein and leads to diffuse localization during prometaphase and metaphase
- Dephosphorylation of CDCA2 by PP2A is necessary for CDCA2/PP1 complex reformation
- The CDCA2/PP1 complex is required for chromatin binding and dephosphorylation of histone H3 at Thr3, Ser10, and Ser28
- The CDCA2/PP1 complex is also involved in nuclear envelope reformation during mitotic exit for proper progression through the M/G1 transition
- The interaction of CDCA2 with importin beta and Nup153, which is required for nuclear envelope formation, is negatively regulated by CDK phosphorylation of the amino-terminal domain of CDCA2
- CDCA2 may play a role in DNA repair as the release of CDCA2 from chromatin at sites of DNA damage promotes the activation of DNA damage response
- These results imply that the CDCA2/PP1 complex may play a part in cancer progression
- Research studies indicate that CDCA2 may serve as a prognostic marker, as increased CDCA2 expression is seen in a number of cancers, including melanoma, neuroblastoma tumors, squamous cell carcinoma, and synovial sarcomas.
Compare Similar Items
Show Difference
Antigen: CDCA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDCA2
Gene Alias: 2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 157313
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q69YH5
Gene Symbols: CDCA2
Immunogen: Synthesized peptide derived from the Internal region of human Repo-Man.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CDCA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDCA2
Gene Alias:
2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
157313
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q69YH5
Gene Symbols:
CDCA2
Immunogen:
Synthesized peptide derived from the Internal region of human Repo-Man.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RhoBTB3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RHOBTB3
Gene Alias: 1700040C17Rik; 2610033K01Rik; 4930503C18Rik; AI317148; AW208826; Kiaa0878; mKIAA0878; Rho related BTB domain containing 3; RHOBTB 3; RHOBTB3; Rho-related BTB domain containing 3; rho-related BTB domain-containing protein 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22836, 73296
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O94955, Q9CTN4
Gene Symbols: RHOBTB3
Immunogen: Synthesized peptide derived from the Internal region of human RHOBTB3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RhoBTB3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RHOBTB3
Gene Alias:
1700040C17Rik; 2610033K01Rik; 4930503C18Rik; AI317148; AW208826; Kiaa0878; mKIAA0878; Rho related BTB domain containing 3; RHOBTB 3; RHOBTB3; Rho-related BTB domain containing 3; rho-related BTB domain-containing protein 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22836, 73296
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O94955, Q9CTN4
Gene Symbols:
RHOBTB3
Immunogen:
Synthesized peptide derived from the Internal region of human RHOBTB3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RPL12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RPL12
Gene Alias: 60S ribosomal protein L12; E430018F03; L12; Large ribosomal subunit protein uL11; ribosomal protein L12; Rpl12
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 269261, 499782, 6136
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P23358, P30050, P35979
Gene Symbols: RPL12
Immunogen: Synthesized peptide derived from the Internal region of human Ribosomal Protein L12.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RPL12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RPL12
Gene Alias:
60S ribosomal protein L12; E430018F03; L12; Large ribosomal subunit protein uL11; ribosomal protein L12; Rpl12
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
269261, 499782, 6136
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P23358, P30050, P35979
Gene Symbols:
RPL12
Immunogen:
Synthesized peptide derived from the Internal region of human Ribosomal Protein L12.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RPL17
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rpl17
Gene Alias: 60S ribosomal protein L17; 60S ribosomal protein L23; Amino acid starvation-induced protein; ASI; gene encoding putative NFkB activating protein; L17; L23; Large ribosomal subunit protein uL22; MGC117162; PD-1; ribosomal protein L17; RPL17; RPL23
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 291434, 319195, 6139
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P18621, P24049, Q9CPR4
Gene Symbols: Rpl17
Immunogen: Synthesized peptide derived from the Internal region of human Ribosomal Protein L17.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RPL17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rpl17
Gene Alias:
60S ribosomal protein L17; 60S ribosomal protein L23; Amino acid starvation-induced protein; ASI; gene encoding putative NFkB activating protein; L17; L23; Large ribosomal subunit protein uL22; MGC117162; PD-1; ribosomal protein L17; RPL17; RPL23
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
291434, 319195, 6139
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P18621, P24049, Q9CPR4
Gene Symbols:
Rpl17
Immunogen:
Synthesized peptide derived from the Internal region of human Ribosomal Protein L17.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG