PA551158

CHMP3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA551158-Each-of-1 In Stock ₹ 44,705.10

PA551158 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CHMP3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CHMP3

Gene Alias

25.1; 25.1 protein; 4921505F14Rik; 9130011K15Rik; CGI149; CGI-149; CGI-49; Charged multivesicular body protein 3; CHMP family, member 3; CHMP3; Chromatin-modifying protein 3; D6Ertd286e; hVps24; NEDF; Neuroendocrine differentiation factor; rVps24p; vacuolar protein sorting 24; vacuolar protein sorting 24 homolog; vacuolar protein sorting-associated protein 24; vacuolar protein-sorting-associated protein 24; Vps24; Vps24p protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51652

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1.7 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9Y3E7

Gene Symbols

CHMP3

Immunogen

Full length fusion protein of human CHMP3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total CHMP3 protein
  • Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs
  • MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids
  • The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes
  • ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released
  • The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses)
  • ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4
  • Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns(3,5)P2 and PtdIns(3,4)P2 in preference to other phosphoinositides tested
  • Involved in late stages of cytokinesis
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  • Isoform 2 prevents stress- mediated cell death and accumulation of reactive oxygen species when expressed in yeast cells.

Compare Similar Items

Show Difference

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Thermo Scientific

PA551158

--


Antigen:
CHMP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHMP3

Gene Alias:
25.1; 25.1 protein; 4921505F14Rik; 9130011K15Rik; CGI149; CGI-149; CGI-49; Charged multivesicular body protein 3; CHMP family, member 3; CHMP3; Chromatin-modifying protein 3; D6Ertd286e; hVps24; NEDF; Neuroendocrine differentiation factor; rVps24p; vacuolar protein sorting 24; vacuolar protein sorting 24 homolog; vacuolar protein sorting-associated protein 24; vacuolar protein-sorting-associated protein 24; Vps24; Vps24p protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51652

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1.7 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9Y3E7

Gene Symbols:
CHMP3

Immunogen:
Full length fusion protein of human CHMP3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PA551161

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Antigen:
VPS37A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Vps37a

Gene Alias:
2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e; ESCRT-I complex subunit VPS37A; HCRP1; Hepatocellular carcinoma-related protein 1; hVps37A; polyglutamine binding protein 2; PQBP2; SPG53; vacuolar protein sorting 37 homolog A; vacuolar protein sorting 37 homolog A (S. cerevisiae); vacuolar protein sorting 37A; vacuolar protein sorting 37A (yeast); vacuolar protein sorting-associated protein 37A; Vps37A; VPS37A, ESCRT-I subunit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
137492

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q8NEZ2

Gene Symbols:
Vps37a

Immunogen:
Fusion protein of human VPS37A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA551164

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Antigen:
WDR45

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WDR45

Gene Alias:
JM5; NBIA4; NBIA5; neurodegeneration with brain iron accumulation 4; neurodegeneration with brain iron accumulation 5; WD repeat domain 45; WD repeat domain phosphoinositide-interacting protein 4; WD repeat domain, X-linked 1; WD repeat-containing protein 45; WD45 repeat protein interacting with phosphoinositides 4; WDR45; WDRX1; WDRXI4; WIPI4; WIPI-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11152

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9Y484

Gene Symbols:
WDR45

Immunogen:
Fusion protein of human WDR45

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA551166

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Antigen:
DCAF7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCAF7

Gene Alias:
1700012F10Rik; 2610037L01Rik; AN11; AN11 homolog; C86529; DCAF7; DDB1 and CUL4 associated factor 7; DDB1- and CUL4-associated factor 7; dirty south; dys; fj83g06; HAN11; han11l; human anthocyanin; RGD1305140; seven-WD-repeat protein of the AN11 family-1; SWAN-1; Unknown (protein for MGC:134591); WD repeat domain 68; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; wdr68; WD-repeat protein; wu:fj83g06; zgc:63940

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10238, 71833

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P61962, P61963

Gene Symbols:
DCAF7

Immunogen:
Fusion protein of human DCAF7

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG