PI187430

ZO-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI187430-Each-of-1 In Stock ₹ 51,531.00

PI187430 - Each of 1

₹ 51,531.00

In Stock

Quantity

1

Base Price: ₹ 51,531.00

GST (18%): ₹ 9,275.58

Total Price: ₹ 60,806.58

Antigen

ZO-1

Classification

Polyclonal

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.4

Gene Accession No.

Q07157

Gene Symbols

TJP1

Immunogen

Peptide sequence from the N-terminal region of human ZO-1.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Gene

TJP1

Gene Alias

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

7082

Content And Storage

4° C

Form

Liquid

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Description

  • Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells
  • Many of the tight junction-associated proteins are members of the membrane- associated guanylate kinase (MAGUK) family and include occludin, ZO-1, ZO-2 and ZO-3
  • These proteins are thought to have both structural and signaling roles, and are characteristically defined by three protein-protein interaction modules: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain
  • ZO-1 forms complexes with either ZO-2 or ZO-3
  • In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction
  • ZO-1 expression is significantly reduced in many breast cancer lines
  • ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue
  • ZO-1 Polyclonal antibody specifically detects ZO-1 in Human samples
  • It is validated for Immunocytochemistry, Immunohistochemistry (Paraffin).

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PI187430

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Antigen:
ZO-1

Classification:
Polyclonal

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Peptide sequence from the N-terminal region of human ZO-1.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Gene:
TJP1

Gene Alias:
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
4° C

Form:
Liquid

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