PI700384

Connexin 46 Recombinant Rabbit Monoclonal Antibody (11H16L33), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PI700384-Each-of-1 In Stock ₹ 48,640.86

PI700384 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Connexin 46

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q64448

Gene Symbols

GJA3

Immunogen

A peptide corresponding to amino acids 131-144 of Q64448.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

11H16L33

Conjugate

Unconjugated

Gene

GJA3

Gene Alias

alpha 3 connexin; Cnx46; connexin 46; connexin-46; CTRCT14; Cx43; CX46; Cxn-46; CZP3; gap junction alpha 3; gap junction alpha-3 protein; gap junction membrane channel protein alpha 3; gap junction protein alpha 3; gap junction protein, alpha 3; gap junction protein, alpha 3, 46kDa; Gja3; Gja-3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14611

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with rat and hamster based on sequence homology
  • Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Connexin 46 (Cx46), also known as Gap Junction Protein Alpha-3 (GJA3), CAE3, CX46 and C2P3, maps to human chromosome 13q11-q12 and encodes a 46 kDa protein
  • Cx46, along with Cx50, is principally expressed in the lens of the eye
  • Cx46 mediates intercellular interactions during development and is necessary for the survival of neural crest cells
  • Cx46 forms gap junctions that connect lens fiber cells and are crucial for maintaining lens transparency and normal lens function
  • Mutations of Cx46 result in severe cataracts of the lens
  • Individual knockouts of Cx46 and Cx50 lead to changes in the rate of lens fiber cell differentiation and cell size, thus the interaction of Cx46 and Cx50 is required for proper organization of fiber cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PI700384

--


Antigen:
Connexin 46

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q64448

Gene Symbols:
GJA3

Immunogen:
A peptide corresponding to amino acids 131-144 of Q64448.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
11H16L33

Conjugate:
Unconjugated

Gene:
GJA3

Gene Alias:
alpha 3 connexin; Cnx46; connexin 46; connexin-46; CTRCT14; Cx43; CX46; Cxn-46; CZP3; gap junction alpha 3; gap junction alpha-3 protein; gap junction membrane channel protein alpha 3; gap junction protein alpha 3; gap junction protein, alpha 3; gap junction protein, alpha 3, 46kDa; Gja3; Gja-3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14611

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI700392

--


Antigen:
Phospho-AKT1 (Ser473)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P31749, P31750

Gene Symbols:
AKT1

Immunogen:
A peptide corresponding to amino acids 468-477 of P31749.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
98H9L8

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11651, 207

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI700393

--


Antigen:
Phospho-IR/IGF1R (Tyr1162, Tyr1163)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P06213, P08069

Gene Symbols:
IGF1R, Insr

Immunogen:
A peptide corresponding to amino acids 1186-1197 and 1162-1173 of P06213 and P08069, respectively

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Clone:
97H9L7

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3480, 3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI700397

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Antigen:
Phospho-4EBP1 (Thr46)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q13541

Gene Symbols:
EIF4EBP1

Immunogen:
A peptide corresponding to amino acids 43-56 of Q13541.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
34H90L46

Conjugate:
Unconjugated

Gene:
EIF4EBP1

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid