Phospho-AMPK alpha-1,2 (Thr183, Thr172) Recombinant Rabbit Monoclonal Antibody (10H2L20), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI701068-Each-of-1 | In Stock | ₹ 55,143.42 |
PI701068 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,143.42
GST (18%): ₹ 9,925.816
Total Price: ₹ 65,069.236
Antigen
Phospho-AMPK alpha-1,2 (Thr183, Thr172)
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P54646, Q13131
Gene Symbols
PRKAA1, PRKAA2
Immunogen
Phosphopeptide corresponding to amino acids 168–178 of human AMPK alpha
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
10H2L20
Conjugate
Unconjugated
Gene
PRKAA2
Gene Alias
2310008I11Rik; 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase alpha-2 catalytic subunit; 5'-AMP-activated protein kinase catalytic alpha-2 subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; 63 kDa subunit; A830082D05; AAPK2; ACACA kinase; acetyl-CoA carboxylase kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase; AMP-activated protein kinase alpha 2; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMP-activated protein kinase alpha-2 variant B; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha 2; AMPK alpha-1 chain; AMPK alpha-2 chain; AMPK subunit alpha-1; AMPK subunit alpha-2; AMPK1; AMPK2; AMPKa1; AMPKa2; AMPK-activated protein kinase alpha-2 subunit; AMPKalpha1; AMPK-alpha-1 chain; AMPKalpha2; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; pAMPK; PRKAA; Prkaa1; Prkaa2; protein kinase; protein kinase AMP-activated alpha 2 catalytic subunit; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase AMP-activated catalytic subunit alpha 2; protein kinase, AMP-activated, alpha 1 catalytic subunit; protein kinase, AMP-activated, alpha 2 catalytic subunit; tau-protein kinase PRKAA1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5562, 5563
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK)
- AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
- AMPK is an important energy-sensing enzyme that monitors cellular energy status
- In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
- Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
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Antigen: Phospho-AMPK alpha-1,2 (Thr183, Thr172)
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P54646, Q13131
Gene Symbols: PRKAA1, PRKAA2
Immunogen: Phosphopeptide corresponding to amino acids 168–178 of human AMPK alpha
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 10H2L20
Conjugate: Unconjugated
Gene: PRKAA2
Gene Alias: 2310008I11Rik; 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase alpha-2 catalytic subunit; 5'-AMP-activated protein kinase catalytic alpha-2 subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; 63 kDa subunit; A830082D05; AAPK2; ACACA kinase; acetyl-CoA carboxylase kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase; AMP-activated protein kinase alpha 2; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMP-activated protein kinase alpha-2 variant B; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha 2; AMPK alpha-1 chain; AMPK alpha-2 chain; AMPK subunit alpha-1; AMPK subunit alpha-2; AMPK1; AMPK2; AMPKa1; AMPKa2; AMPK-activated protein kinase alpha-2 subunit; AMPKalpha1; AMPK-alpha-1 chain; AMPKalpha2; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; pAMPK; PRKAA; Prkaa1; Prkaa2; protein kinase; protein kinase AMP-activated alpha 2 catalytic subunit; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase AMP-activated catalytic subunit alpha 2; protein kinase, AMP-activated, alpha 1 catalytic subunit; protein kinase, AMP-activated, alpha 2 catalytic subunit; tau-protein kinase PRKAA1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5562, 5563
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen: Phospho-INSR (Tyr1158)
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P06213
Gene Symbols: INSR
Immunogen: Phosphopeptide corresponding to amino acids 1153–1162 of human insulin receptor
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 8H20L22
Conjugate: Unconjugated
Gene: INSR
Gene Alias: 4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3643
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen: IL-27 p28
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q8NEV9
Gene Symbols: Il27
Immunogen: Recombinant protein corresponding to amino acids 20–189 of human IL-27
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 7H7L10
Conjugate: Unconjugated
Gene: Il27
Gene Alias: IL27; IL-27; IL-27 p28 subunit; IL-27 subunit alpha; Il27a; IL-27A; IL-27-A; IL27-A; IL27p28; IL-27p28; IL30; IL-30; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27; interleukin-27 subunit alpha; Interleukin-30; p28
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 246778
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
