PI701108
STAT5 alpha Recombinant Rabbit Monoclonal Antibody (6H2L9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI701108-Each-of-1 | In Stock | ₹ 53,047.20 |
PI701108 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,047.20
GST (18%): ₹ 9,548.496
Total Price: ₹ 62,595.696
Antigen
STAT5 alpha
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P42229
Gene Symbols
STAT5A
Immunogen
Peptide corresponding to amino acids 50–58 of human signal transducer and activator of transcription 5a (this region has no sequence homology with other STATs)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Western Blot
Clone
6H2L9
Conjugate
Unconjugated
Gene
STAT5A
Gene Alias
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6776
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- STAT5 alpha is a member of the STAT family of transcription factors
- In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
- STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
- Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
- The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
- STAT5 alpha, along with STAT5 beta, were identified in mouse
- The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
- However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
- STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.
Compare Similar Items
Show Difference
Antigen: STAT5 alpha
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P42229
Gene Symbols: STAT5A
Immunogen: Peptide corresponding to amino acids 50–58 of human signal transducer and activator of transcription 5a (this region has no sequence homology with other STATs)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Western Blot
Clone: 6H2L9
Conjugate: Unconjugated
Gene: STAT5A
Gene Alias: AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6776
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
STAT5 alpha
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P42229
Gene Symbols:
STAT5A
Immunogen:
Peptide corresponding to amino acids 50–58 of human signal transducer and activator of transcription 5a (this region has no sequence homology with other STATs)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Western Blot
Clone:
6H2L9
Conjugate:
Unconjugated
Gene:
STAT5A
Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6776
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: STAT6
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P42226, P52633
Gene Symbols: STAT6
Immunogen: Peptide corresponding to amino acids 630–638 of human singal transducer and activator of transcription 6
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 21HCLC
Conjugate: Unconjugated
Gene: STAT6
Gene Alias: 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20852, 6778
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
STAT6
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P42226, P52633
Gene Symbols:
STAT6
Immunogen:
Peptide corresponding to amino acids 630–638 of human singal transducer and activator of transcription 6
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
21HCLC
Conjugate:
Unconjugated
Gene:
STAT6
Gene Alias:
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20852, 6778
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IL-21
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9HBE4
Gene Symbols: IL21
Immunogen: Recombinant protein corresponding to amino acids 37–162 of human IL-21
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: 18H2L4
Conjugate: Unconjugated
Gene: IL21
Gene Alias: CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 59067
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IL-21
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9HBE4
Gene Symbols:
IL21
Immunogen:
Recombinant protein corresponding to amino acids 37–162 of human IL-21
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
18H2L4
Conjugate:
Unconjugated
Gene:
IL21
Gene Alias:
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
59067
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CXCL9
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P18340, Q07325
Gene Symbols: CXCL9
Immunogen: Recombinant protein corresponding to amino acids 23–125 of human monokine induced by Interferon-gamma
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 11H1L14
Conjugate: Unconjugated
Gene: CXCL9
Gene Alias: BB139920; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 9; CMK; crg-10; CXC; CXC motif chemokine; C-X-C motif chemokine 9; C-X-C motif chemokine ligand 9; CXCL; CXCL9; gamma interferon-induced monokine; gamma-interferon-induced monokine; HuMIG; M119; Mig; monokine induced by gamma interferon; monokine induced by interferon gamma; monokine induced by interferon-gamma; MuMIG; protein m119; SCYB9; small inducible cytokine B subfamily (Cys-X-Cys), member 9; small inducible cytokine B9; small-inducible cytokine B9
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17329, 4283
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CXCL9
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P18340, Q07325
Gene Symbols:
CXCL9
Immunogen:
Recombinant protein corresponding to amino acids 23–125 of human monokine induced by Interferon-gamma
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
11H1L14
Conjugate:
Unconjugated
Gene:
CXCL9
Gene Alias:
BB139920; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 9; CMK; crg-10; CXC; CXC motif chemokine; C-X-C motif chemokine 9; C-X-C motif chemokine ligand 9; CXCL; CXCL9; gamma interferon-induced monokine; gamma-interferon-induced monokine; HuMIG; M119; Mig; monokine induced by gamma interferon; monokine induced by interferon gamma; monokine induced by interferon-gamma; MuMIG; protein m119; SCYB9; small inducible cytokine B subfamily (Cys-X-Cys), member 9; small inducible cytokine B9; small-inducible cytokine B9
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17329, 4283
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid