PI701151
p21 Recombinant Rabbit Monoclonal Antibody (2H2L13), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI701151-Each-of-1 | In Stock | ₹ 54,929.52 |
PI701151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,929.52
GST (18%): ₹ 9,887.314
Total Price: ₹ 64,816.834
Antigen
p21
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P38936
Gene Symbols
CDKN1A
Immunogen
Peptide from human p21 protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
2H2L13
Conjugate
Unconjugated
Gene
CDKN1A
Gene Alias
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1026
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with equine, mouse, rabbit and rat based on sequence homology
- Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Protein p21 is a tumor suppressor protein which is an inhibitor of Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53
- P21 is important in the response of cells to genotoxic stress and a major transcriptional target of p53 protein
- The occurrence of p21 in the nucleus executes binding and inhibition activity of cyclin dependent kinases Cdk1 and Cdk2, and blocks the transition from G1 phase into S phase or from G2 phase into mitosis after DNA damage, which enables the repair of damaged DNA
- In the cytoplasm, p21 protein has an anti-apoptotic effect
- P21 is able to bind to and inhibit caspase 3, as well as the apoptotic kinases ASK1 and JNK
- P21 exhibits a dual function in carcinogenesis, and acts as a tumor suppressor, prevents apoptosis, and acts as an oncogene.
Compare Similar Items
Show Difference
Antigen: p21
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P38936
Gene Symbols: CDKN1A
Immunogen: Peptide from human p21 protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 2H2L13
Conjugate: Unconjugated
Gene: CDKN1A
Gene Alias: Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1026
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
p21
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P38936
Gene Symbols:
CDKN1A
Immunogen:
Peptide from human p21 protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
2H2L13
Conjugate:
Unconjugated
Gene:
CDKN1A
Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1026
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: LMO2
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P25791
Gene Symbols: Lmo2
Immunogen: Recombinant protein corresponding to amino acids 1–127 of human LMO2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 13H1L2
Conjugate: Unconjugated
Gene: Lmo2
Gene Alias: cysteine-rich protein TTG-2; LIM domain only 2; LIM domain only 2 (rhombotin-like 1); LIM domain only protein 2; LIM domain only-2; LIM only 2; LMO2; LMO-2; LMO2 protein; Rbtn2; Rbtn-2; RBTNL1; RHOM2; Rhom-2; rhombotin 2; rhombotin-2; rhombotin-like 1; si:dkey-10o6.5; T-cell translocation gene 2; T-cell translocation protein 2; TTG2; wu:fc83a08; zgc:111930; zlmo2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4005
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
LMO2
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P25791
Gene Symbols:
Lmo2
Immunogen:
Recombinant protein corresponding to amino acids 1–127 of human LMO2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
13H1L2
Conjugate:
Unconjugated
Gene:
Lmo2
Gene Alias:
cysteine-rich protein TTG-2; LIM domain only 2; LIM domain only 2 (rhombotin-like 1); LIM domain only protein 2; LIM domain only-2; LIM only 2; LMO2; LMO-2; LMO2 protein; Rbtn2; Rbtn-2; RBTNL1; RHOM2; Rhom-2; rhombotin 2; rhombotin-2; rhombotin-like 1; si:dkey-10o6.5; T-cell translocation gene 2; T-cell translocation protein 2; TTG2; wu:fc83a08; zgc:111930; zlmo2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4005
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Rex1
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q96MM3
Gene Symbols: ZFP42
Immunogen: Recombinant protein corresponding to amino acids 1–140 of human REX1 transcription factor
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 14H16L9
Conjugate: Unconjugated
Gene: ZFP42
Gene Alias: 1700021P10Rik; 2610511M11Rik; AW050347; ELOABP1; EloA-BP1; elongin A binding protein 1; elongin A-binding protein 1; elongin-A-binding protein 1; hREX-1; KIAA1138; mREX-1; reduced expression protein 1; REX1; Rex-1; REX1 transcription factor; REX1, RNA exonuclease 1 homolog; REX1, RNA exonuclease 1 homolog (S. cerevisiae); REXO1; RNA exonuclease 1 homolog; Tceb3bp1; transcription elongation factor B polypeptide 3 binding protein 1; transcription elongation factor B polypeptide 3-binding protein 1; Zfp42; Zfp-42; ZFP42 zinc finger protein; Zfp971; Zinc finger protein 42; zinc finger protein 42 homolog; Zinc finger protein 754; zinc finger protein 971; ZNF754
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100856057, 132625
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Rex1
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q96MM3
Gene Symbols:
ZFP42
Immunogen:
Recombinant protein corresponding to amino acids 1–140 of human REX1 transcription factor
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
14H16L9
Conjugate:
Unconjugated
Gene:
ZFP42
Gene Alias:
1700021P10Rik; 2610511M11Rik; AW050347; ELOABP1; EloA-BP1; elongin A binding protein 1; elongin A-binding protein 1; elongin-A-binding protein 1; hREX-1; KIAA1138; mREX-1; reduced expression protein 1; REX1; Rex-1; REX1 transcription factor; REX1, RNA exonuclease 1 homolog; REX1, RNA exonuclease 1 homolog (S. cerevisiae); REXO1; RNA exonuclease 1 homolog; Tceb3bp1; transcription elongation factor B polypeptide 3 binding protein 1; transcription elongation factor B polypeptide 3-binding protein 1; Zfp42; Zfp-42; ZFP42 zinc finger protein; Zfp971; Zinc finger protein 42; zinc finger protein 42 homolog; Zinc finger protein 754; zinc finger protein 971; ZNF754
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100856057, 132625
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Occludin
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q16625
Gene Symbols: OCLN
Immunogen: Peptide corresponding to amino acids 387–403 of human occludin
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 6H10L9
Conjugate: Unconjugated
Gene: OCLN
Gene Alias: AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100506658
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Occludin
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q16625
Gene Symbols:
OCLN
Immunogen:
Peptide corresponding to amino acids 387–403 of human occludin
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
6H10L9
Conjugate:
Unconjugated
Gene:
OCLN
Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100506658
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid