PI710446

MEK1 Recombinant Polyclonal Antibody (22HCLC), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI710446-Each-of-1 In Stock ₹ 46,501.86

PI710446 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

MEK1

Classification

Recombinant Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q02750

Gene Symbols

Map2k1

Immunogen

Peptide corresponding to amino acids 31–50 of human MEK1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

22HCLC

Conjugate

Unconjugated

Gene

Map2k1

Gene Alias

CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5604

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation
  • MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx
  • Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1
  • It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines
  • Mutations in the gene can lead to cardiofaciocutaneous syndrome.

Compare Similar Items

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Img

Thermo Scientific

PI710446

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Antigen:
MEK1

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q02750

Gene Symbols:
Map2k1

Immunogen:
Peptide corresponding to amino acids 31–50 of human MEK1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
22HCLC

Conjugate:
Unconjugated

Gene:
Map2k1

Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5604

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI710448

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Antigen:
Granzyme B

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P10144

Gene Symbols:
GZMB

Immunogen:
Peptide corresponding to amino acids 26–38 of human Granzyme B

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
23HCLC

Conjugate:
Unconjugated

Gene:
GZMB

Gene Alias:
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3002

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI710449

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Antigen:
SRC

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P05480, P12931

Gene Symbols:
SRC

Immunogen:
Peptide corresponding to amino acids 30–45 of human SRC

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
14HCLC

Conjugate:
Unconjugated

Gene:
SRC

Gene Alias:
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene; wu:fc54g04; XELAEV_18046582mg; xsrc

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20779, 6714

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI710452

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Antigen:
ErbB2 (HER-2)

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P04626

Gene Symbols:
ERBB2

Immunogen:
Peptide corresponding to amino acids 33–46 of human ERBB2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
7HCLC

Conjugate:
Unconjugated

Gene:
ERBB2

Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2064

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid