PI711180
Bora Recombinant Polyclonal Antibody (10HCLC), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI711180-Each-of-1 | In Stock | ₹ 42,822.78 |
PI711180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,822.78
GST (18%): ₹ 7,708.10
Total Price: ₹ 50,530.88
Antigen
Bora
Classification
Recombinant Polyclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q6PGQ7, Q8BS90
Gene Symbols
BORA
Immunogen
Protein corresponding to Human BORA (aa 274-456)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
10HCLC
Conjugate
Unconjugated
Gene
BORA
Gene Alias
6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
77744, 79866
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- This antibody is predicted to react with Monkey, Horse, Bovine and Sheep Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
- They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
- While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
- The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
- Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation during mitosis
- Bora is localized to the nucleus until mitosis is initiated, then translocates to the cytoplasm in a Cdc2 dependent manner
- Activation of Cdc2 initiates the release of Bora into the cytoplasm where it can bind and activate ARK-1
- PLK1 (polo-like kinase-1) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation by ARK-1
- Bora and ARK-1 cooperatively activate PLK1 and control mitotic entry
- Bora mutants result in multipolar spindles in mitosis identical to those observed when ARK-1 function is blocked
- Thus, the ARK1-Bora-PLK1 regulatory circuit in mammalian cells elucidates a key mechanism in cell cycle regulation
- At least three isoforms of Bora are known to exist.
Compare Similar Items
Show Difference
Antigen: Bora
Classification: Recombinant Polyclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q6PGQ7, Q8BS90
Gene Symbols: BORA
Immunogen: Protein corresponding to Human BORA (aa 274-456)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 10HCLC
Conjugate: Unconjugated
Gene: BORA
Gene Alias: 6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 77744, 79866
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Bora
Classification:
Recombinant Polyclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q6PGQ7, Q8BS90
Gene Symbols:
BORA
Immunogen:
Protein corresponding to Human BORA (aa 274-456)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
10HCLC
Conjugate:
Unconjugated
Gene:
BORA
Gene Alias:
6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
77744, 79866
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RAD1
Classification: Recombinant Polyclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: O60671
Gene Symbols: RAD1
Immunogen: Protein corresponding to Human RAD1 (aa 133-282)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 8HCLC
Conjugate: Unconjugated
Gene: RAD1
Gene Alias: cell cycle checkpoint protein Hrad1; cell cycle checkpoint protein RAD1; checkpoint control protein HRAD1; DNA repair exonuclease rad1 homolog; DNA repair exonuclease REC1; exonuclease homolog RAD1; hRAD1; mRAD1; RAD1; RAD1 checkpoint clamp component; RAD1 checkpoint DNA exonuclease; RAD1 homolog; RAD1 homolog (S. pombe); rad1-like DNA damage checkpoint protein; REC1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5810
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RAD1
Classification:
Recombinant Polyclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
O60671
Gene Symbols:
RAD1
Immunogen:
Protein corresponding to Human RAD1 (aa 133-282)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
8HCLC
Conjugate:
Unconjugated
Gene:
RAD1
Gene Alias:
cell cycle checkpoint protein Hrad1; cell cycle checkpoint protein RAD1; checkpoint control protein HRAD1; DNA repair exonuclease rad1 homolog; DNA repair exonuclease REC1; exonuclease homolog RAD1; hRAD1; mRAD1; RAD1; RAD1 checkpoint clamp component; RAD1 checkpoint DNA exonuclease; RAD1 homolog; RAD1 homolog (S. pombe); rad1-like DNA damage checkpoint protein; REC1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5810
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-Claudin 3 (Thr192)
Classification: Recombinant Polyclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: O15551
Gene Symbols: CLDN3
Immunogen: Peptide corresponding to Human CLDN3 (aa 187-195)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 4HCLC
Conjugate: Unconjugated
Gene: CLDN3
Gene Alias: AI182374; C7orf1; claudin 3; claudin-3; CLDN3; clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-R2; CPE-receptor 2; CPETR2; hRVP1; integral membrane protein claudin-3; mRVP1; Rat ventral prostate.1 protein; Rat ventral prostate.1 protein homolog; RVP1; tight junction protein; ventral prostate.1 protein; ventral prostate.1 protein homolog; ventral prostate.1-like protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1365
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-Claudin 3 (Thr192)
Classification:
Recombinant Polyclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
O15551
Gene Symbols:
CLDN3
Immunogen:
Peptide corresponding to Human CLDN3 (aa 187-195)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
4HCLC
Conjugate:
Unconjugated
Gene:
CLDN3
Gene Alias:
AI182374; C7orf1; claudin 3; claudin-3; CLDN3; clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-R2; CPE-receptor 2; CPETR2; hRVP1; integral membrane protein claudin-3; mRVP1; Rat ventral prostate.1 protein; Rat ventral prostate.1 protein homolog; RVP1; tight junction protein; ventral prostate.1 protein; ventral prostate.1 protein homolog; ventral prostate.1-like protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1365
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-c-Raf (Ser621)
Classification: Recombinant Polyclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P04049
Gene Symbols: Raf1
Immunogen: Peptide corresponding to Human RAF1 (aa 618-626)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry
Clone: __
Conjugate: Unconjugated
Gene: Raf1
Gene Alias: 6430402F14Rik; AA990557; BB129353; CMD1NN; CRAF; C-RAF; C-Raf proto-oncogene, serine/threonine kinase; Craf1; Craf1 transforming; D830050J10Rik; EC 2.7.11.1; kinase Raf1; murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); murine sarcoma 3611 oncogene 1; NS5; Oncogene RAF1; OTTHUMP00000207813; OTTHUMP00000209389; proto-oncogene c-RAF; RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; RAF1; Raf-1; Raf-1 proto-oncogene, serine/threonine kinase; sarcoma 3611 oncogene; v-Raf; v-raf-1 leukemia viral oncogene 1; vraf1 murine le; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1; v-raf-leukemia viral oncogene 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5894
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-c-Raf (Ser621)
Classification:
Recombinant Polyclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P04049
Gene Symbols:
Raf1
Immunogen:
Peptide corresponding to Human RAF1 (aa 618-626)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry
Clone:
__
Conjugate:
Unconjugated
Gene:
Raf1
Gene Alias:
6430402F14Rik; AA990557; BB129353; CMD1NN; CRAF; C-RAF; C-Raf proto-oncogene, serine/threonine kinase; Craf1; Craf1 transforming; D830050J10Rik; EC 2.7.11.1; kinase Raf1; murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); murine sarcoma 3611 oncogene 1; NS5; Oncogene RAF1; OTTHUMP00000207813; OTTHUMP00000209389; proto-oncogene c-RAF; RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; RAF1; Raf-1; Raf-1 proto-oncogene, serine/threonine kinase; sarcoma 3611 oncogene; v-Raf; v-raf-1 leukemia viral oncogene 1; vraf1 murine le; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1; v-raf-leukemia viral oncogene 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5894
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid