PI711542

MNK1 Recombinant Polyclonal Antibody (6HCLC), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI711542-Each-of-1 In Stock ₹ 42,993.90

PI711542 - Each of 1

₹ 42,993.90

In Stock

Quantity

1

Base Price: ₹ 42,993.90

GST (18%): ₹ 7,738.902

Total Price: ₹ 50,732.802

Antigen

MNK1

Classification

Recombinant Polyclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

O08605, Q9BUB5

Gene Symbols

MKNK1

Immunogen

Peptides corresponding to human MNK1 (aa38-57, aa9-26)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

6HCLC

Conjugate

Unconjugated

Gene

MKNK1

Gene Alias

2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

17346, 8569

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • This antibody is predicted to react with Monkey, Mouse, Cat Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production
  • The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis
  • Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo
  • Mnk2 may play a role in the response to environmental stress and cytokines
  • Expression of active mutants of MNK1 and MNK2 in 293 cells diminishes cap-dependent translation relative to cap-independent translation in a transient reporter assay
  • Human Mnk2 is homologous to murine Mnk2 (approximately 94% identical) and human Mnk1 (71% identical)
  • In vitro phosphorylation studies show that Mnk2 is a significantly better substrate than Mnk1 for extracellular signal-regulated kinase 2 (Erk2), p38MAPKalpha, and p38MAPKbeta.

Compare Similar Items

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Thermo Scientific

PI711542

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Antigen:
MNK1

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O08605, Q9BUB5

Gene Symbols:
MKNK1

Immunogen:
Peptides corresponding to human MNK1 (aa38-57, aa9-26)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
6HCLC

Conjugate:
Unconjugated

Gene:
MKNK1

Gene Alias:
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17346, 8569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI711549

--


Antigen:
SMYD3

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9H7B4

Gene Symbols:
SMYD3

Immunogen:
Protein corresponding to human SMYD3 (aa1-aa428)

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
SMYD3

Gene Alias:
2410008A19Rik; bA74P14.1; bA74P14.1 (novel protein); histone-lysine N-methyltransferase SMYD3; KMT3E; SET and MYND domain containing 3; SET and MYND domain-containing protein 3; Smyd3; Zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; zinc finger, MYND domain containing 1; ZMYND1; ZNFN3A1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64754

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI711565

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Antigen:
TWIST1

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q15672

Gene Symbols:
TWIST1

Immunogen:
Protein corresponding to human TWIST1 (aa1-aa100)

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
TWIST1

Gene Alias:
AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska<m10Jus>; Ska<sup>m10Jus</sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7291

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI711569

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Antigen:
ANP

Classification:
Recombinant Polyclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01160, P01161, P05125

Gene Symbols:
NPPA

Immunogen:
Peptide corresponding to human ANP (aa127- 145)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
17 HCLC

Conjugate:
Unconjugated

Gene:
NPPA

Gene Alias:
Anf; ANP; ATFB6; atrial natriuretic factor; Atrial natriuretic peptide; atriopeptin; Atriopeptin I; Atriopeptin II; Atriopeptin III; Atriopeptin-1; Atriopeptin-2; Atriopeptin-3; ATRST2; Auriculin-A; Auriculin-B; Cardiodilatin; Cardiodilatin-related peptide; cardionatrin; CDD; CDD-ANF; CDP; natriuretic peptide A; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor A variant 1; natriuretic peptide precursor A variant NPPA-M1; natriuretic peptide precursor A variant NPPA-M2; natriuretic peptide precursor A variant NPPA-M3; natriuretic peptide precursor type A; natriuretic peptide type A; natriuretic peptides A; Nppa; Pnd; Prepronatriodilatin; Pronatriodilatin; RATANF; urodilatin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
230899, 24602, 4878

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid