PI720206

PRDM16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI720206-Each-of-1 In Stock ₹ 48,640.86

PI720206 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

PRDM16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRDM16

Gene Alias

5730557K01Rik; CMD1LL; csp1; Histone-lysine N-methyltransferase PRDM16; Kiaa1675; line 27; LVNC8; MDS1/EVI1-like gene 1; MEL1; PFM13; PR domain 16; PR domain containing 16; PR domain zinc finger protein 16; PR domain-containing protein 16; Prdm16; Transcription factor MEL1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100366024, 63976, 70673

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

A2A935, Q9HAZ2

Gene Symbols

PRDM16

Immunogen

Peptides corresponding to human PRDM16/MEL1 (236-251, 23-40)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • This antibody is predicted to react with Monkey, Mouse, Dog PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain
  • The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML)
  • This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36, q21)-positive MDS/AML
  • The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML
  • Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway
  • Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells.

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Thermo Scientific

PI720206

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Antigen:
PRDM16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRDM16

Gene Alias:
5730557K01Rik; CMD1LL; csp1; Histone-lysine N-methyltransferase PRDM16; Kiaa1675; line 27; LVNC8; MDS1/EVI1-like gene 1; MEL1; PFM13; PR domain 16; PR domain containing 16; PR domain zinc finger protein 16; PR domain-containing protein 16; Prdm16; Transcription factor MEL1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100366024, 63976, 70673

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
A2A935, Q9HAZ2

Gene Symbols:
PRDM16

Immunogen:
Peptides corresponding to human PRDM16/MEL1 (236-251, 23-40)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PI720207

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Antigen:
SMN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMN1

Gene Alias:
AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6606

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q16637

Gene Symbols:
SMN1

Immunogen:
Protein corresponding to Human SMN1 (aa 2-294)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PI720212

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Antigen:
NSUN4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NSUN4

Gene Alias:
2310010O12Rik; 2810405F18Rik; 5-methylcytosine rRNA methyltransferase NSUN4; AI507900; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; NOP2/Sun RNA methyltransferase family member 4; Nsun4; putative methyltransferase NSUN4; RGD1559652; RP4-603I14.2; SHTAP; Sperm head and tail associated protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
387338

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q96CB9

Gene Symbols:
NSUN4

Immunogen:
Protein corresponding to Human NSUN4 (aa 26-384)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PI720219

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Antigen:
RBPJ

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBPJ

Gene Alias:
AI843960; AOS3; CBF1; CBF-1; csl; H-2K binding factor-2; Igkjrb; Igkjrb1; Igkrsbp; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; KBF2; Rbpj; RBP-J; RBP-J kappa; RBPJK; RBP-JK; rbp-jkappa; RBPSUH; recombination signal binding protein for immunoglobulin kappa J region; recombining binding protein suppressor of hairless; recombining binding protein suppressor of hairless-like; recombining binding protein suppressor of hairless-like protein; renal carcinoma antigen NY-REN-30; SUH; suppressor of hairless homolog; Unknown (protein for MGC:128782)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3516

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q06330

Gene Symbols:
RBPJ

Immunogen:
Protein corresponding to Human RBPJ (aa 1-200)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG