PIMA110146

IGF2R Monoclonal Antibody (MEM-238), APC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA110146-Each-of-1 In Stock ₹ 43,507.26

PIMA110146 - Each of 1

₹ 43,507.26

In Stock

Quantity

1

Base Price: ₹ 43,507.26

GST (18%): ₹ 7,831.307

Total Price: ₹ 51,338.567

Antigen

IGF2R

Classification

Monoclonal

Conjugate

APC

Gene

IGF2R

Gene Alias

300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3482

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

MEM-238

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P11717

Gene Symbols

IGF2R

Immunogen

Recombinant Vaccinia virus encoding CD222.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

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Description

  • This antibody recognizes an epitope between domains 2 and 5 of CD222 (IGF2 receptor), a ubiquitously expressed 250 kDa multifunctional type I transmembrane protein
  • The majority of CD222 is found in the late endosomal/prelysosomal compartment, 5-10% in the plasma membrane and the truncated (220 kDa) form of CD222 is present in human and bovine serum
  • Lysosomal enzymes containing one or two mannose 6-phosphate (man6P) moieties are moved about in the cell by two distinct but interconnected cycles by means of approximately 300 kDa cation independent mannose 6-phospate receptors (CI-MPR)
  • The biosynthetic cycle refers to the MPR transport of newly synthesized lysosomal enzymes from the trans Golgi network to late endosomes or early lysosomes
  • The endocytic cycle transports extracellular lysosomal enzymes from the plasma membrane via clathrin-coated vesicles to early endosomes
  • The entire pool of MPRs cycles between these cellular compartments every 3 hours
  • The steady state distribution of MPR's is predominantly within late endosomes, fewer in the trans Golgi network and approximately 10 % at cell surface
  • In addition to its man6P binding activity, the MPR contains a separate binding site for the type II insulin-like growth factor and is capable of binding both man6P and IGF-II simultaneously
  • An approximately 240 kDa soluble, truncated form, representing the extracellular domain of the protein, has also been found circulating in serum and is capable of binding both ligands.

Compare Similar Items

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Thermo Scientific

PIMA110146

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Antigen:
IGF2R

Classification:
Monoclonal

Conjugate:
APC

Gene:
IGF2R

Gene Alias:
300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3482

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-238

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P11717

Gene Symbols:
IGF2R

Immunogen:
Recombinant Vaccinia virus encoding CD222.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA110148

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Antigen:
IGF2R

Classification:
Monoclonal

Conjugate:
PE

Gene:
IGF2R

Gene Alias:
300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3482

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-238

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P11717

Gene Symbols:
IGF2R

Immunogen:
Recombinant Vaccinia virus encoding CD222.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA110152

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Antigen:
PrP

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PRNP

Gene Alias:
AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; AltPrP; ASCR; BSE; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; major prion protein; alternative prion protein; major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor; prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; Prnp; Prn-p; PrP; PrP<C>; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5621

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Clone:
EM-20

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
F7VJQ1, P04156

Gene Symbols:
PRNP

Immunogen:
Recombinant human prion protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA110157

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Antigen:
CD26

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
DPP4

Gene Alias:
ACT3; Activation molecule 3; ADABP; ADCP2; ADCP-2; ADCP-I; adenosine deaminase complexing protein; Adenosine deaminase complexing protein 2; bile canaliculus domain-specific membrane glycoprotein; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 60 kDa soluble form; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV 60 kDa soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidylpeptidase 4; dipeptidyl-peptidase 4; dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2); dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP4; Dpp-4; DPPIV; DPP-IV; GP110 glycoprotein; I79_016618; serine protease; T-cell activation antigen CD26; THAM; Thymocyte-activating molecule; TP103; WC10

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1803

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Flow Cytometry

Clone:
BA5b

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P27487

Gene Symbols:
DPP4

Immunogen:
A human T cell clone

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a