PIMA110239

CD47 Monoclonal Antibody (MEM-122), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA110239-Each-of-1 In Stock ₹ 36,448.56

PIMA110239 - Each of 1

₹ 36,448.56

In Stock

Quantity

1

Base Price: ₹ 36,448.56

GST (18%): ₹ 6,560.741

Total Price: ₹ 43,009.301

Antigen

CD47

Classification

Monoclonal

Conjugate

FITC

Gene

CD47

Gene Alias

9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

397042, 961

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

MEM-122

Formulation

TBS with 0.2% BSA and 15mM sodium azide; pH 8

Gene Accession No.

Q08722, Q9GKE8

Gene Symbols

CD47

Immunogen

COS-7 (African green monkey) cells

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Non-human Primate, Porcine

Product Type

Antibody

Isotype

IgM

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Description

  • CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions
  • Engagement of CD47 by soluble ligands or counter receptors modulates various signaling pathways, such as activation of heterotrimeric G proteins
  • Functionally, CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix
  • CD47 is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction
  • CD47 has broad tissue distribution, is reduced in expression on Rh erythrocytes
  • CD47 acts as a ligand for CD172a (signal regulatory protein alpha, SIRP alpha), an immune inhibitory receptor on macrophages; this interaction prevents phagocytosis of CD47-positive cells
  • Moreover, CD47-CD172a system affects cell migration, B cell adhesion, T cell activation, and is involved in modulation of chondrocyte responses to mechanical signals, and promotes neuronal development, being especially abundant in synapse-rich regions of brain and retina.

Compare Similar Items

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Img

Thermo Scientific

PIMA110239

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Antigen:
CD47

Classification:
Monoclonal

Conjugate:
FITC

Gene:
CD47

Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
397042, 961

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-122

Formulation:
TBS with 0.2% BSA and 15mM sodium azide; pH 8

Gene Accession No.:
Q08722, Q9GKE8

Gene Symbols:
CD47

Immunogen:
COS-7 (African green monkey) cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgM

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PIMA110244

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Antigen:
ICAM-3

Classification:
Monoclonal

Conjugate:
PE

Gene:
ICAM3

Gene Alias:
CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3385

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-171

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P32942

Gene Symbols:
ICAM3

Immunogen:
Human granulocytes

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA110245

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Antigen:
CD52

Classification:
Monoclonal

Conjugate:
APC

Gene:
CD52

Gene Alias:
AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1043

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HI186

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P31358

Gene Symbols:
CD52

Immunogen:
Human tonsil

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

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PIMA110247

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Antigen:
CD53

Classification:
Monoclonal

Conjugate:
FITC

Gene:
Cd53

Gene Alias:
AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
963

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-53

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P19397

Gene Symbols:
Cd53

Immunogen:
Leukocytes of pacient suffering from a LGL-type leukemia.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1