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PIMA110355

HLA-E Monoclonal Antibody (MEM-E/07), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA110355-Each-of-1 In Stock ₹ 48,384.18

PIMA110355 - Each of 1

₹ 48,384.18

In Stock

Quantity

1

Base Price: ₹ 48,384.18

GST (18%): ₹ 8,709.152

Total Price: ₹ 57,093.332

Antigen

HLA-E

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P13747

Gene Symbols

HLA-E

Immunogen

Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

MEM-E/07

Conjugate

Biotin

Gene

HLA-E

Gene Alias

A29 protein; antigen presenting molecule; Aw-33; Aw-74; DAMA-277I14.1; DAQB-90C11.16; DKFZp686P19218; EA1.2; EA2.1; FLJ26655; HLA A; HLA class I antigen; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, E alpha chain; HLA locus; HLA-6.2; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLA-DQB1; HLA-DRB1; HLAE; HLA-E; Human leukocyte antigen A; leukocyte antigen class I-A; lymphocyte antigen; major histocompatibility complex, class I, A; major histocompatibility complex, class I, E; MCH class I antigen; MHC; MHC 1; MHC class 1 antigen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen E; MHC class I antigen heavy chain; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen null protein; MHC class I antigene; MHC class II antigen; MHC classI antigen; MHC HLA-E alpha-1; MHC HLA-E alpha-2.1; MHC1; QA1; sHLA-E; Soluble HLA class I histocompatibility antigen, alpha chain E; truncated MHC class I antigen

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3133

Content And Storage

4° C, do not freeze

Form

Liquid

Description

  • This antibody reacts with some classical MHC Class I molecules (MHC Class Ia): HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly)
  • HLA-E belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules
  • The heavy chain is approximately 45 kDa and its gene contains 8 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

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Img

Thermo Scientific

PIMA110355

--

Antigen:
HLA-E
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P13747
Gene Symbols:
HLA-E
Immunogen:
Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
MEM-E/07
Conjugate:
Biotin
Gene:
HLA-E
Gene Alias:
A29 protein; antigen presenting molecule; Aw-33; Aw-74; DAMA-277I14.1; DAQB-90C11.16; DKFZp686P19218; EA1.2; EA2.1; FLJ26655; HLA A; HLA class I antigen; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, E alpha chain; HLA locus; HLA-6.2; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLA-DQB1; HLA-DRB1; HLAE; HLA-E; Human leukocyte antigen A; leukocyte antigen class I-A; lymphocyte antigen; major histocompatibility complex, class I, A; major histocompatibility complex, class I, E; MCH class I antigen; MHC; MHC 1; MHC class 1 antigen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen E; MHC class I antigen heavy chain; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen null protein; MHC class I antigene; MHC class II antigen; MHC classI antigen; MHC HLA-E alpha-1; MHC HLA-E alpha-2.1; MHC1; QA1; sHLA-E; Soluble HLA class I histocompatibility antigen, alpha chain E; truncated MHC class I antigen
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3133
Content And Storage:
4° C, do not freeze
Form:
Liquid

Img

Thermo Scientific

PIMA110357

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Antigen:
HLA-G (soluble)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P17693
Gene Symbols:
HLA-G
Immunogen:
C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
5A6G7
Conjugate:
Unconjugated
Gene:
HLA-G
Gene Alias:
acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3135
Content And Storage:
4° C, do not freeze
Form:
Liquid

Img

Thermo Scientific

PIMA110358

--

Antigen:
HLA-G (soluble)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P17693
Gene Symbols:
HLA-G
Immunogen:
C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
2A12
Conjugate:
Unconjugated
Gene:
HLA-G
Gene Alias:
acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species:
Mouse
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3135
Content And Storage:
4° C, do not freeze
Form:
Liquid

Img

Thermo Scientific

PIMA110361

--

Antigen:
HLA-G
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P17693
Gene Symbols:
HLA-G
Immunogen:
HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
87G
Conjugate:
Biotin
Gene:
HLA-G
Gene Alias:
acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3135
Content And Storage:
4° C, do not freeze
Form:
Liquid