PIMA113042
STAT3 Monoclonal Antibody (9D8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA113042-Each-of-1 | In Stock | ₹ 51,934.92 |
PIMA113042 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,934.92
GST (18%): ₹ 9,348.286
Total Price: ₹ 61,283.206
Antigen
STAT3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P40763, P42227, P52631
Gene Symbols
STAT3
Immunogen
Residues 655-770 from human recombinant protein expressed in bacteria
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
9D8
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20848, 25125, 6774
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-13042 detects STAT3 from human, mouse, monkey and rat samples
- MA1-13042 has been successfully used in Western blot, ChIP, immunofluorescence, immunohistochemistry (paraffin), and immunoprecipitation procedures
- By Western blot, this antibody detects a 88 kDa protein corresponding to STAT3
- Positive control: HepG2 cells
- The MA1-13042 antigen is a recombinant protein corresponding to residues 655-770 of human STAT3
- Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit
- This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays
- It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications
- Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
Compare Similar Items
Show Difference
Antigen: STAT3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P40763, P42227, P52631
Gene Symbols: STAT3
Immunogen: Residues 655-770 from human recombinant protein expressed in bacteria
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 9D8
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20848, 25125, 6774
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
STAT3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P40763, P42227, P52631
Gene Symbols:
STAT3
Immunogen:
Residues 655-770 from human recombinant protein expressed in bacteria
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
9D8
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 25125, 6774
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BID
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P55957, P70444
Gene Symbols: BID
Immunogen: Residues 5-195 from human recombinant protein expressed in bacteria
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 23F7
Conjugate: Unconjugated
Gene: BID
Gene Alias: 2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12122, 637
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BID
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P55957, P70444
Gene Symbols:
BID
Immunogen:
Residues 5-195 from human recombinant protein expressed in bacteria
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
23F7
Conjugate:
Unconjugated
Gene:
BID
Gene Alias:
2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12122, 637
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Calpain 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide; pH 7.2-7.4
Gene Accession No.: O35350, P07384
Gene Symbols: CAPN1
Immunogen: human erythrocyte Calpain-1 large subunit
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: P-6(2H7)
Conjugate: Unconjugated
Gene: CAPN1
Gene Alias: calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12333, 823
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Calpain 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide; pH 7.2-7.4
Gene Accession No.:
O35350, P07384
Gene Symbols:
CAPN1
Immunogen:
human erythrocyte Calpain-1 large subunit
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
P-6(2H7)
Conjugate:
Unconjugated
Gene:
CAPN1
Gene Alias:
calcium activated neutral protease; calcium-activated neutral protease 1; calcium-activated neutral proteinase 1; calcium-dependent protease; calpain; calpain 1; calpain 1 large subunit; calpain 1, (mu/I) large subunit; calpain 1, large subunit; calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP; CANP 1; Canp1; CANPL1; Capa1; Capa-1; Capn1; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; Cls1; I79_024883; micromolar calcium-activated neutral protease 1; micromolar calcium-activated neutral protease 1 isoform A; micromolar calcium-activated neutral protease 1 isoform B; micromolar calcium-dependent neutral protease large subunit; micromolar-calpain; mucalpain; mu-calpain; mu-calpin; muCANP; muCL; PIG30; SPG76
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12333, 823
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Nesprin 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: Q6ZWR6
Gene Symbols: SYNE1
Immunogen: Recombinant protein containing residues RKLESTLTGLEQSRERQERR
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 6A
Conjugate: Unconjugated
Gene: SYNE1
Gene Alias: 8B; A330049M09Rik; ARCA1; BE692247; C130039F11Rik; C6orf98; CPG2; CPG2 full length; dJ45H2.2; DKFZp781J13156; EDMD4; enaptin; enaptin165; FLJ30878; FLJ41140; KASH domain-containing protein 1; KASH1; KIAA0796; KIAA1262; KIAA1756; mKIAA1756; MYNE1; Myne-1; Myocyte nuclear envelope protein 1; Nesp1; nesprin 1; nesprin-1; Nuclear envelope spectrin repeat protein 1; RP1-130E4.2; SCAR8; spectrin repeat containing nuclear envelope protein 1; spectrin repeat containing, nuclear envelope 1; synaptic nuclear envelope 1; synaptic nuclear envelope protein 1; synaptic nuclei expressed gene 1; SYNE 1; SYNE1; Syne-1; syne-1 fragment
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 499010, 64009
Content And Storage: -20°C
Form: Liquid
Antigen:
Nesprin 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
Q6ZWR6
Gene Symbols:
SYNE1
Immunogen:
Recombinant protein containing residues RKLESTLTGLEQSRERQERR
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
6A
Conjugate:
Unconjugated
Gene:
SYNE1
Gene Alias:
8B; A330049M09Rik; ARCA1; BE692247; C130039F11Rik; C6orf98; CPG2; CPG2 full length; dJ45H2.2; DKFZp781J13156; EDMD4; enaptin; enaptin165; FLJ30878; FLJ41140; KASH domain-containing protein 1; KASH1; KIAA0796; KIAA1262; KIAA1756; mKIAA1756; MYNE1; Myne-1; Myocyte nuclear envelope protein 1; Nesp1; nesprin 1; nesprin-1; Nuclear envelope spectrin repeat protein 1; RP1-130E4.2; SCAR8; spectrin repeat containing nuclear envelope protein 1; spectrin repeat containing, nuclear envelope 1; synaptic nuclear envelope 1; synaptic nuclear envelope protein 1; synaptic nuclei expressed gene 1; SYNE 1; SYNE1; Syne-1; syne-1 fragment
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
499010, 64009
Content And Storage:
-20°C
Form:
Liquid