PIMA1134

RhoA Monoclonal Antibody (1B8-1C7), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA1134-Each-of-1 In Stock ₹ 49,282.56

PIMA1134 - Each of 1

₹ 49,282.56

In Stock

Quantity

1

Base Price: ₹ 49,282.56

GST (18%): ₹ 8,870.861

Total Price: ₹ 58,153.421

Antigen

RhoA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P61586, P61589, Q9QUI0

Gene Symbols

RHOA

Immunogen

Full-length recombinant His-tagged human RhoA

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

1B8-1C7

Conjugate

Unconjugated

Gene

RHOA

Gene Alias

Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; h12; h6; H9; MGC72339; MST081; MSTP081; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog A1; ras homolog A2; ras homolog family member A; ras homolog family member B; ras homolog family member C; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member B; ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 12; Rho cDNA clone 6; rho cDNA clone 9; Rho family GTPase; RHO12; Rhoa; RHOB; RHOC; rhoC GTPase; RHOH12; RHOH6; RHOH9; rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; small GTP binding protein RhoA; small GTP binding protein RhoC; transforming protein RhoA

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

117273, 11848, 387

Content And Storage

-20°C

Form

Liquid

Description

  • By Western blot, MA1-134 detects recombinant RhoA, but not recombinant RhoB or recombinant RhoC
  • By Western blot on mouse and rat kidney whole tissue lysates, MA1-134 detects a band of ∽22kD corresponding to the expected molecular weight of RhoA
  • A nonspecific band at ∽55kD was also detected in both kidney lysates
  • RhoA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers
  • It is involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis, and plays an essential role in cleavage furrow formation
  • RhoA is required for the apical junction formation of keratinocyte cell-cell adhesion, and serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders
  • RhoA stimulates PKN2 kinase activity and may be an activator of PLCE1
  • It is activated by ARHGEF2, which promotes the exchange of GDP for GTP
  • It is essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly
  • The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex
  • It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity
  • In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

Compare Similar Items

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Img

Thermo Scientific

PIMA1134

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Antigen:
RhoA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P61586, P61589, Q9QUI0

Gene Symbols:
RHOA

Immunogen:
Full-length recombinant His-tagged human RhoA

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
1B8-1C7

Conjugate:
Unconjugated

Gene:
RHOA

Gene Alias:
Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; h12; h6; H9; MGC72339; MST081; MSTP081; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog A1; ras homolog A2; ras homolog family member A; ras homolog family member B; ras homolog family member C; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member B; ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 12; Rho cDNA clone 6; rho cDNA clone 9; Rho family GTPase; RHO12; Rhoa; RHOB; RHOC; rhoC GTPase; RHOH12; RHOH6; RHOH9; rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; small GTP binding protein RhoA; small GTP binding protein RhoC; transforming protein RhoA

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
117273, 11848, 387

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA1135

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Antigen:
6x-His Tag

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Mixture of N-terminal and C-terminal 6x-His peptides, CG-HHHHHH and HHHHHH-GC

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
4E3D10H2/E3

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
6His tag; 6X His; His Tag; Histidine Tag

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA1135HRP

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Antigen:
6x-His Tag

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with proprietary stabilizer and 0.07% Kathon

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Mixture of N-terminal and C-terminal 6x-His peptides, CG-HHHHHH and HHHHHH-GC

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
4E3D10H2/E3

Conjugate:
HRP

Gene:
__

Gene Alias:
6His tag; 6X His; His Tag; Histidine Tag

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA1138

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Antigen:
BRCA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Recombinant full length human BRCA1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunoprecipitation, Western Blot

Clone:
MS13

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
brca 1; Brca1; brca-1; BRCA1, DNA repair associated; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; breast cancer 1; breast cancer 1 early onset; breast cancer 1, early onset; breast cancer associated 1; breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; BROVCA1; BROVCA12; Delta772-3095; early onset breast cancer 1; Fanconi anemia, complementation group S; FANCS; IRIS; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; PNCA4; PPP1R53; protein phosphatase 1, regulatory subunit 53; PSCP; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1; RNF53; truncated BRCA1; truncated breast and ovarian cancer susceptibility protein 1; truncated breast and ovarian cancer sususceptibility protein 1; truncated breast cancer type 1 susceptibility protein

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
-20°C

Form:
Liquid