PIMA1157

PKC alpha Monoclonal Antibody (MC5), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA1157-Each-of-1 In Stock ₹ 48,170.28

PIMA1157 - Each of 1

₹ 48,170.28

In Stock

Quantity

1

Base Price: ₹ 48,170.28

GST (18%): ₹ 8,670.65

Total Price: ₹ 56,840.93

Antigen

PKC alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.

P04409, P05696, P10102, P17252, P20444

Gene Symbols

PRKCA

Immunogen

Purified bovine brain Protein Kinase C alpha.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Human, Mouse, Non-human Primate, Rabbit, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

MC5

Conjugate

Unconjugated

Gene

PRKCA

Gene Alias

AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100037720, 18750, 24680, 282001, 490904, 5578

Content And Storage

-20°C

Form

Liquid

Description

  • Western blot analysis of MA1-157 detects an ∽80 kDa protein in human, bovine, non-human primate, mouse, rat, dog and rabbit cells
  • In Jurkat, rat brain and MDCK cell lysates, a weak unknown band at ∽140 kDa is also detected
  • MA1-157 shows specificity to PKC alpha and is non-reactive to other PKC family members
  • The PKC family of serine/threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol
  • PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
  • PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters
  • Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells
  • The protein encoded by this gene is one of the PKC family members
  • This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control
  • Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

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Thermo Scientific

PIMA1157

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Antigen:
PKC alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P04409, P05696, P10102, P17252, P20444

Gene Symbols:
PRKCA

Immunogen:
Purified bovine brain Protein Kinase C alpha.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Non-human Primate, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MC5

Conjugate:
Unconjugated

Gene:
PRKCA

Gene Alias:
AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100037720, 18750, 24680, 282001, 490904, 5578

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA1159

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Antigen:
N-cadherin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P15116, P19022

Gene Symbols:
CDH2

Immunogen:
MBP fusion protein containing the full cytoplasmic domain of human N-cadherin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
13A9

Conjugate:
Unconjugated

Gene:
CDH2

Gene Alias:
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1000, 12558

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA1163

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Antigen:
CCR7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P32248, P47774

Gene Symbols:
Ccr7

Immunogen:
Rat basophilic leukaemia (RBL)-2H3 transfectants expressing mouse CCR7

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
__

Isotype:
IgG2a

Applications:
Flow Cytometry, Western Blot

Clone:
4B12

Conjugate:
Unconjugated

Gene:
Ccr7

Gene Alias:
BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1236, 12775

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA1164

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Antigen:
LAMP1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P11279, P11438, P14562, P49129

Gene Symbols:
LAMP1

Immunogen:
Rat liver lysosomal membrane preparations

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
LY1C6

Conjugate:
Unconjugated

Gene:
LAMP1

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100689406, 16783, 25328, 3916

Content And Storage:
-20°C

Form:
Liquid