PIMA119761

CD27 Monoclonal Antibody (LT27), APC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA119761-Each-of-1 In Stock ₹ 43,250.58

PIMA119761 - Each of 1

₹ 43,250.58

In Stock

Quantity

1

Base Price: ₹ 43,250.58

GST (18%): ₹ 7,785.104

Total Price: ₹ 51,035.684

Antigen

CD27

Classification

Monoclonal

Conjugate

APC

Gene

CD27

Gene Alias

CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

939

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

LT27

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P26842

Gene Symbols

CD27

Immunogen

Human peripheral blood lymphocytes.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Description

  • CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
  • The TNF superfamily members are known for the regulation of cell proliferation and death
  • In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
  • High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
  • CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
  • CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
  • Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
  • Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
  • RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
  • CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
  • Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.

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Img

Thermo Scientific

PIMA119761

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Antigen:
CD27

Classification:
Monoclonal

Conjugate:
APC

Gene:
CD27

Gene Alias:
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
939

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
LT27

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P26842

Gene Symbols:
CD27

Immunogen:
Human peripheral blood lymphocytes.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA119762

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Antigen:
ITGB1

Classification:
Monoclonal

Conjugate:
PE

Gene:
ITGB1

Gene Alias:
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3688, 397019, 477956

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-101A

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P05556, Q9GLP0

Gene Symbols:
ITGB1

Immunogen:
Raji Burkitt's lymphoma cell line.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Canine, Human, Porcine

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA119764

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Antigen:
CD3

Classification:
Monoclonal

Conjugate:
PerCP

Gene:
Cd247

Gene Alias:
4930549J05Rik; A430104F18Rik; AI504783; antigen CD3D, delta polypeptide (TiT3 complex); antigen CD3E, epsilon polypeptide (TiT3 complex); antigen CD3G, gamma polypeptide; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; CD3; CD3 antigen delta chain; CD3 antigen delta polypeptide; CD3 antigen gamma chain; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 antigen, zeta polypeptide; CD3 delta; CD3 epsilon; CD3 epsilon chain; CD3 epsilon subunit; CD3 epsilon subunit precursor; CD3 gamma-chain; CD3 glycoprotein; CD3 glycoprotein precursor; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; CD3 protein; CD3 TCR complex; CD3 type I transmembrane glycoprotein; CD3 type I transmembrane glycoprotein precursor; CD3 zeta chain; Cd3d; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3E antigen, epsilon polypeptide; CD3E antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; Cd3-eta; Cd3g; CD3G antigen, gamma polypeptide; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Cd3h; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; Ctg3; Ctg-3; FLJ18683; IMD17; IMD18; IMD19; IMD25; Leu-4; OKT3, delta chain; T cell antigen receptor complex epsilon subunit of T3; T3/TCR complex; T3d; T3e; T3g; T3Z; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 epsilon chain; T-cell receptor CD3 epsilon subunit; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 delta chain; T-cell receptor T3 eta chain; T-cell receptor T3 gamma chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; T-cell surface glycoprotein CD3 zeta chain; T-cell surface protein; TcR CD3 delta-chain; TcR CD3 gamma-chain; TCR zeta chain; TCR zeta chain subunit; TCRE; Tcrk; TCRZ; TCRzeta; TiT3 complex; type I transmembrane protein; T-cell surface molecule CD3

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
915, 916, 917, 919

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-57

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P04234, P07766, P09693, P20963

Gene Symbols:
Cd247, Cd3d, CD3E, CD3g

Immunogen:
Human thymocytes and T lymphocytes.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Thermo Scientific

PIMA119767

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Antigen:
CD30

Classification:
Monoclonal

Conjugate:
APC

Gene:
TNFRSF8

Gene Alias:
Ber-H2; Cd30; CD30 antigen; CD30 molecule; CD30L receptor; cytokine receptor CD30; D1S166E; Ki; Ki-1; Ki-1 antigen; Lymphocyte activation antigen CD30; sCD30; soluble CD30; TNF receptor superfamily member 8; TNFRSF8; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8; Tumor necrosis factor superfamily member 8; tumor necrosis factor superfamily, member CD30

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-268

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
Expression vector containing CD30 cDNA (booster suspension of THP-1 cell line).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG