PIMA120347

CD254 (RANK Ligand) Monoclonal Antibody (12A380), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA120347-Each-of-1 In Stock ₹ 45,132.90

PIMA120347 - Each of 1

₹ 45,132.90

In Stock

Quantity

1

Base Price: ₹ 45,132.90

GST (18%): ₹ 8,123.922

Total Price: ₹ 53,256.822

Antigen

CD254 (RANK Ligand)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O14788, O35235

Gene Symbols

TNFSF11

Immunogen

Fusion protein containing amino acid residues 1-317 of human TRANCE/RANKL.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

12A380

Conjugate

Unconjugated

Gene

TNFSF11

Gene Alias

CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21943, 8600

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-20347 detects sRANKL in Human and Mouse samples
  • This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
  • This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
  • T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
  • This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
  • Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
  • The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
  • Two alternatively spliced transcript variants have been found.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA120347

--


Antigen:
CD254 (RANK Ligand)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O14788, O35235

Gene Symbols:
TNFSF11

Immunogen:
Fusion protein containing amino acid residues 1-317 of human TRANCE/RANKL.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
12A380

Conjugate:
Unconjugated

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21943, 8600

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA120378

--


Antigen:
Agrin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.:
A2ASQ1, P25304

Gene Symbols:
Agrn

Immunogen:
Recombinant rat agrin, C-terminal construct.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
Agr 33

Conjugate:
Unconjugated

Gene:
Agrn

Gene Alias:
AGR; Agrin; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 22 kDa fragment; Agrin C-terminal 90 kDa fragment; Agrin N-terminal 110 kDa subunit; agrin proteoglycan; Agrn; C22; C90; CMS8; CMSPPD; nmf380; RP23-139J18.2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11603, 25592

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA120380

--


Antigen:
Agrin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative

Gene Accession No.:
A2ASQ1, P25304

Gene Symbols:
Agrn

Immunogen:
Recombinant rat agrin, C-terminal construct.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry

Clone:
Agr 247

Conjugate:
Unconjugated

Gene:
Agrn

Gene Alias:
AGR; Agrin; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 22 kDa fragment; Agrin C-terminal 90 kDa fragment; Agrin N-terminal 110 kDa subunit; agrin proteoglycan; Agrn; C22; C90; CMS8; CMSPPD; nmf380; RP23-139J18.2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11603, 25592

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA1204

--


Antigen:
SFTPB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P07988

Gene Symbols:
SFTPB

Immunogen:
Recombinant Surfactant Protein B

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Western Blot

Clone:
SPB02 (1B9)

Conjugate:
Unconjugated

Gene:
SFTPB

Gene Alias:
18 kDa pulmonary-surfactant protein; 6 kDa protein; AI562151; P SFTB3; pot. surfactant-associated protein precursor; putative; preproprotein; PSP-B; Pulmonary surfactant protein 18; pulmonary surfactant protein B; pulmonary surfactant-associated protein B; pulmonary surfactant-associated protein B precursor; pulmonary surfactant-associated protein B; LOW QUALITY PROTEIN: pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SF-B; SFPB; SFTB3; SFTP3; Sftp-3; Sftpb; SMDP1; SP 18; SP-B; SPBS; surfactant associated protein B; surfactant protein B; surfactant protein-B; surfactant pulmonary-associated protein B; surfactant, pulmonary-associated protein B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6439

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid