PIMA121391

SHP-1 Monoclonal Antibody (PTY15), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA121391-Each-of-1 In Stock ₹ 45,560.70

PIMA121391 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

SHP-1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

0.01M PBS with no preservative; pH 7.2

Gene Accession No.

P29350

Gene Symbols

PTPN6

Immunogen

Recombinant full length protein (Human).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

PTY15

Conjugate

Unconjugated

Gene

PTPN6

Gene Alias

70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5777

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • MA1-21391 detects SHP1 in Human samples
  • SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
  • The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
  • SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
  • In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
  • Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
  • Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA121391

--


Antigen:
SHP-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.01M PBS with no preservative; pH 7.2

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
Recombinant full length protein (Human).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
PTY15

Conjugate:
Unconjugated

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA121392

--


Antigen:
Colorectal Carcinoma

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Tissue / cell preparation (Human).

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
Y94

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA121394

--


Antigen:
SAA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P0DJI8

Gene Symbols:
SAA1

Immunogen:
Highly purified recombinant human SAA (MW: 12 kDa)

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Western Blot

Clone:
291

Conjugate:
Unconjugated

Gene:
SAA1

Gene Alias:
amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA121397

--


Antigen:
SAA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P0DJI8

Gene Symbols:
SAA1

Immunogen:
Highly purified recombinant human SAA (MW: 12 kDa)

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Western Blot

Clone:
585

Conjugate:
Unconjugated

Gene:
SAA1

Gene Alias:
amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid