PIMA121486
SHP-1 Monoclonal Antibody (PTY10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA121486-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA121486 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
SHP-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P29350
Gene Symbols
PTPN6
Immunogen
Recombinant full length protein (Human).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
PTY10
Conjugate
Unconjugated
Gene
PTPN6
Gene Alias
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5777
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
- The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
- SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
- In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
- Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
- Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.
Compare Similar Items
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Antigen: SHP-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P29350
Gene Symbols: PTPN6
Immunogen: Recombinant full length protein (Human).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: PTY10
Conjugate: Unconjugated
Gene: PTPN6
Gene Alias: 70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5777
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SHP-1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P29350
Gene Symbols:
PTPN6
Immunogen:
Recombinant full length protein (Human).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
PTY10
Conjugate:
Unconjugated
Gene:
PTPN6
Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5777
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SAA
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P0DJI8
Gene Symbols: SAA1
Immunogen: Highly purified recombinant human serum amyloid A (MW: 12 kDa).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: 115
Conjugate: Unconjugated
Gene: SAA1
Gene Alias: amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6288
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SAA
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P0DJI8
Gene Symbols:
SAA1
Immunogen:
Highly purified recombinant human serum amyloid A (MW: 12 kDa).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone:
115
Conjugate:
Unconjugated
Gene:
SAA1
Gene Alias:
amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6288
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: GPBB
Classification: Monoclonal
Concentration: 5.8 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P11216
Gene Symbols: PYGB
Immunogen: Full length, human GPBB protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Affinity Purification, ELISA, Western Blot
Clone: 1G6
Conjugate: Unconjugated
Gene: PYGB
Gene Alias: brain glycogen phosphorylase; glycogen phosphorylase B; glycogen phosphorylase, brain form; GLYPHOA; GPBB; MGC9213; phosphorylase, glycogen; brain; PYGB
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5834
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
GPBB
Classification:
Monoclonal
Concentration:
5.8 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P11216
Gene Symbols:
PYGB
Immunogen:
Full length, human GPBB protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Affinity Purification, ELISA, Western Blot
Clone:
1G6
Conjugate:
Unconjugated
Gene:
PYGB
Gene Alias:
brain glycogen phosphorylase; glycogen phosphorylase B; glycogen phosphorylase, brain form; GLYPHOA; GPBB; MGC9213; phosphorylase, glycogen; brain; PYGB
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5834
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: GPBB
Classification: Monoclonal
Concentration: 2.0 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P11216
Gene Symbols: PYGB
Immunogen: Recombinant full length protein (Human).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Affinity Purification, ELISA, Western Blot
Clone: 6F1
Conjugate: Unconjugated
Gene: PYGB
Gene Alias: brain glycogen phosphorylase; glycogen phosphorylase B; glycogen phosphorylase, brain form; GLYPHOA; GPBB; MGC9213; phosphorylase, glycogen; brain; PYGB
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5834
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
GPBB
Classification:
Monoclonal
Concentration:
2.0 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P11216
Gene Symbols:
PYGB
Immunogen:
Recombinant full length protein (Human).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Affinity Purification, ELISA, Western Blot
Clone:
6F1
Conjugate:
Unconjugated
Gene:
PYGB
Gene Alias:
brain glycogen phosphorylase; glycogen phosphorylase B; glycogen phosphorylase, brain form; GLYPHOA; GPBB; MGC9213; phosphorylase, glycogen; brain; PYGB
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5834
Content And Storage:
4° C, do not freeze
Form:
Liquid