PIMA122084

Leptin Monoclonal Antibody (4F12), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA122084-Each-of-1 In Stock ₹ 45,646.26

PIMA122084 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Leptin

Classification

Monoclonal

Concentration

5.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P41159

Gene Symbols

Lep

Immunogen

Recombinant full length protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

4F12

Conjugate

Unconjugated

Gene

Lep

Gene Alias

CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3952

Content And Storage

4° C

Form

Liquid

Description

  • MA1-22084 detects Leptin in Human samples
  • Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
  • Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
  • Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
  • Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
  • Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
  • Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
  • Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
  • Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
  • Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
  • Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
  • Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.

Compare Similar Items

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Img

Thermo Scientific

PIMA122084

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Antigen:
Leptin

Classification:
Monoclonal

Concentration:
5.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P41159

Gene Symbols:
Lep

Immunogen:
Recombinant full length protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
4F12

Conjugate:
Unconjugated

Gene:
Lep

Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3952

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA122093

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Antigen:
Thyroxine

Classification:
Monoclonal

Concentration:
4.8 mg/mL

Formulation:
TBS with 0.05% sodium azide; pH 7.5

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Full length native protein (purified, Sigma T-2501) conjugated to BSA.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chemical, Mammalia

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA

Clone:
XM212

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA1221

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Antigen:
TTR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P02766

Gene Symbols:
TTR

Immunogen:
Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
2E10C5

Conjugate:
Unconjugated

Gene:
TTR

Gene Alias:
AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7276

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA122147

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Antigen:
Collagen III

Classification:
Monoclonal

Concentration:
2.3 mg/mL

Formulation:
Ascites with 15mM sodium azide

Gene Accession No.:
P02461, P13941

Gene Symbols:
Col3a1

Immunogen:
Human collagen type III protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Dot Blot, ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
FH-7A

Conjugate:
Unconjugated

Gene:
Col3a1

Gene Alias:
alpha1 (III) collagen; alpha-1 collagen type III; alpha-1 type III collagen; alpha-1 type-3 collagen; AW550625; COL 3; COL3; COL3 alpha 1; COL3A1; Col3a-1; collagen; Collagen 3; collagen alpha 1 type III; collagen alpha-1(III) chain; collagen type III alpha 1 chain; collagen, fetal; collagen, type III, alpha 1; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant); collagen, type III, alpha 1 chain, fibril forming; Collagen3; EDS4A; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; mKIAA4231; MMS10-W; Ms10w; PIIINP; pro alpha 1 type III collagen; procollagen, type III, alpha 1; unknown

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100009177, 1281, 84032

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid