PIMA123176

Cdc34 Monoclonal Antibody (90.12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA123176-Each-of-1 In Stock ₹ 45,646.26

PIMA123176 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Cdc34

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

P49427

Gene Symbols

CDC34

Immunogen

Full-length human Cdc34 expressed in E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunoprecipitation, Western Blot

Clone

90.12

Conjugate

Unconjugated

Gene

CDC34

Gene Alias

(E3-independent) E2 ubiquitin-conjugating enzyme R1; AI327276; CDC34; cell division cycle 34; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; serine protease; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme Cdc34; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

997

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recommended positive controls: 293 cells and recombinant fusion protein
  • Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
  • In vitro catalyzes 'Lys-48'-linked polyubiquitination
  • Cooperates with the E2 UBCH5C and the SCF (FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation
  • Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin
  • UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin
  • Cooperates with the SCF (SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1
  • Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles
  • Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation
  • Also involved in the degradation of beta-catenin
  • Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA123176

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Antigen:
Cdc34

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P49427

Gene Symbols:
CDC34

Immunogen:
Full-length human Cdc34 expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunoprecipitation, Western Blot

Clone:
90.12

Conjugate:
Unconjugated

Gene:
CDC34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AI327276; CDC34; cell division cycle 34; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; serine protease; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme Cdc34; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
997

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA123185

--


Antigen:
CENPF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P49454

Gene Symbols:
CENPF

Immunogen:
Protein fragment expressed in E. coli corresponding to amino acids 1759-2093.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
14C10 1D8

Conjugate:
Unconjugated

Gene:
CENPF

Gene Alias:
6530404A22Rik; AH antigen; AI325968; cell-cycle-dependent 350K nuclear protein; CENF; CENPF; CENP-F; CENP-F kinetochore protein; centromere autoantigen F; centromere protein F; centromere protein F, (mitosin); centromere protein F, 350/400ka (mitosin); centromere protein F, 350/400kDa (mitosin); CILD31; hcp-1; im:7140452; im:7144238; im:7154719; im:7156761; kinetochore protein CENPF; Lek1; leucine, glutamic acid, lysine family 1 protein; mitosin; PRO1779; RP11-262H5.1; si:ch211-152h14.2; STROMS

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1063

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA123189

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Antigen:
DNA Ligase I

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P18858, P37913

Gene Symbols:
LIG1

Immunogen:
Full-length recombinant human DNA Ligase I protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
10H5

Conjugate:
Unconjugated

Gene:
LIG1

Gene Alias:
AL033288; DNA ligase (ATP) 1; DNA ligase 1; DNA ligase I; LIG1; Lig-1; ligase 1; ligase I, DNA, ATP-dependent; LigI; MGC117397; MGC130025; polydeoxyribonucleotide synthase [ATP] 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16881, 3978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA123200

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Antigen:
POLD1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and no preservative; pH 7

Gene Accession No.:
P28340, P52431

Gene Symbols:
POLD1

Immunogen:
Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
607

Conjugate:
Unconjugated

Gene:
POLD1

Gene Alias:
125kDa; CDC2; CDC2 homolog; CRCS10; DAN polymerase delta 1, catalytic subunit; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit; DNA polymerase delta, catalytic subunit; DNA polymerase subunit delta p125; DNA-directed DNA polymerase delta 1; MDPL; POL D; POLD; POLD1; polymerase (DNA directed), delta 1, catalytic subunit; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit; Polymerase D

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18971, 5424

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid