PIMA123234
FOXO1 Monoclonal Antibody (7H11), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA123234-Each-of-1 | In Stock | ₹ 45,218.46 |
PIMA123234 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
FOXO1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
Q12778
Gene Symbols
FOXO1
Immunogen
Amino acids 242-655 of FKHR expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgM
Applications
Immunohistochemistry, Western Blot
Clone
7H11
Conjugate
Unconjugated
Gene
FOXO1
Gene Alias
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2308
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recommended positive controls: Cos 1 cells transfected with human FKHR
- FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
- Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
- Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
- Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
- FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
- FOXO1 binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'- TT[G/A]TTTAC-3'
- FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
- Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
- In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
- FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.
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Antigen: FOXO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: Q12778
Gene Symbols: FOXO1
Immunogen: Amino acids 242-655 of FKHR expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Applications: Immunohistochemistry, Western Blot
Clone: 7H11
Conjugate: Unconjugated
Gene: FOXO1
Gene Alias: Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2308
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
FOXO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
Q12778
Gene Symbols:
FOXO1
Immunogen:
Amino acids 242-655 of FKHR expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Applications:
Immunohistochemistry, Western Blot
Clone:
7H11
Conjugate:
Unconjugated
Gene:
FOXO1
Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2308
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Nuclear Matrix Protein p84
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.: P59924, Q8R3N6, Q96FV9
Gene Symbols: Thoc1
Immunogen: Amino acids 15-374 of human p84 expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 5E10
Conjugate: Unconjugated
Gene: Thoc1
Gene Alias: 3110002N20Rik; AW107452; HPR1; hTREX84; I79_014746; LRRGT00070; NMP-84; Nuclear matrix protein p84; P84; P84N5; THO complex 1; THO complex subunit 1; THO complex subunit 1-like protein; tho1; Thoc1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100770844, 225160, 291797, 9984
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Nuclear Matrix Protein p84
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.:
P59924, Q8R3N6, Q96FV9
Gene Symbols:
Thoc1
Immunogen:
Amino acids 15-374 of human p84 expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
5E10
Conjugate:
Unconjugated
Gene:
Thoc1
Gene Alias:
3110002N20Rik; AW107452; HPR1; hTREX84; I79_014746; LRRGT00070; NMP-84; Nuclear matrix protein p84; P84; P84N5; THO complex 1; THO complex subunit 1; THO complex subunit 1-like protein; tho1; Thoc1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100770844, 225160, 291797, 9984
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RbAp48
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q09028, Q60972
Gene Symbols: RBBP4
Immunogen: The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 13D10
Conjugate: Unconjugated
Gene: RBBP4
Gene Alias: CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; histone-binding protein RBBP4; lin-53; mRbAp48; MSI1 protein homolog; nucleosome-remodeling factor subunit RBAP48; NURF55; RB binding protein 4, chromatin remodeling factor; RBAP48; RBBP4; RBBP-4; retinoblastoma binding protein 4; retinoblastoma-binding protein 4; Retinoblastoma-binding protein p48
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 19646, 313048, 5928
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RbAp48
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q09028, Q60972
Gene Symbols:
RBBP4
Immunogen:
The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
13D10
Conjugate:
Unconjugated
Gene:
RBBP4
Gene Alias:
CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; histone-binding protein RBBP4; lin-53; mRbAp48; MSI1 protein homolog; nucleosome-remodeling factor subunit RBAP48; NURF55; RB binding protein 4, chromatin remodeling factor; RBAP48; RBBP4; RBBP-4; retinoblastoma binding protein 4; retinoblastoma-binding protein 4; Retinoblastoma-binding protein p48
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
19646, 313048, 5928
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RbAp46/RbAp48
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.: Q09028, Q16576, Q60972, Q60973
Gene Symbols: RBBP4, RBBP7
Immunogen: The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 15G12
Conjugate: Unconjugated
Gene: RBBP4
Gene Alias: AA409861; AI173248; AU019541; BB114024; CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; G1/S transition control protein-binding protein; G1/S transition control protein-binding protein RbAp46; histone acetyltransferase type B subunit 2; Histone-binding protein RBBP4; histone-binding protein RBBP7; lin-53; mRbAp46; mRbAp48; MSI1 protein homolog; nucleosome-remodeling factor subunit RBAP46; Nucleosome-remodeling factor subunit RBAP48; NURF55; RB binding protein 4, chromatin remodeling factor; RB binding protein 7, chromatin remodeling factor; Rbap46; RBAP48; Rbbp4; RBBP-4; RBBP7; RBBP-7; retinoblastoma binding protein 4; retinoblastoma binding protein 7; retinoblastoma-binding protein 4; Retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; Retinoblastoma-binding protein p48; retinoblastoma-binding protein RbAp46
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 19646, 245688, 5928, 5931
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RbAp46/RbAp48
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.:
Q09028, Q16576, Q60972, Q60973
Gene Symbols:
RBBP4, RBBP7
Immunogen:
The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
15G12
Conjugate:
Unconjugated
Gene:
RBBP4
Gene Alias:
AA409861; AI173248; AU019541; BB114024; CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; G1/S transition control protein-binding protein; G1/S transition control protein-binding protein RbAp46; histone acetyltransferase type B subunit 2; Histone-binding protein RBBP4; histone-binding protein RBBP7; lin-53; mRbAp46; mRbAp48; MSI1 protein homolog; nucleosome-remodeling factor subunit RBAP46; Nucleosome-remodeling factor subunit RBAP48; NURF55; RB binding protein 4, chromatin remodeling factor; RB binding protein 7, chromatin remodeling factor; Rbap46; RBAP48; Rbbp4; RBBP-4; RBBP7; RBBP-7; retinoblastoma binding protein 4; retinoblastoma binding protein 7; retinoblastoma-binding protein 4; Retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; Retinoblastoma-binding protein p48; retinoblastoma-binding protein RbAp46
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
19646, 245688, 5928, 5931
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid