PIMA125493
beta Amyloid Monoclonal Antibody (2C8), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA125493-Each-of-1 | In Stock | ₹ 43,036.68 |
PIMA125493 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,036.68
GST (18%): ₹ 7,746.602
Total Price: ₹ 50,783.282
Antigen
beta Amyloid
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and no preservative; pH 7.2
Gene Accession No.
P05067, P12023
Gene Symbols
APP
Immunogen
Synthetic peptide corresponding to residues 1-16 of beta Amyloid.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
2C8
Conjugate
Unconjugated
Gene
APP
Gene Alias
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; be
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11820, 351
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- This antibody reacts with synthetic beta amyloid (Abeta 40 and Abeta 42) in Western blots
- Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
- Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
- The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
- Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
- Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
- The remnant protein is processed by another protease, gamma-secretase
- Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
- Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
- The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
- Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
- Alzheimer’s disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
- Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.
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Antigen: beta Amyloid
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and no preservative; pH 7.2
Gene Accession No.: P05067, P12023
Gene Symbols: APP
Immunogen: Synthetic peptide corresponding to residues 1-16 of beta Amyloid.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 2C8
Conjugate: Unconjugated
Gene: APP
Gene Alias: A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; be
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11820, 351
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
beta Amyloid
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and no preservative; pH 7.2
Gene Accession No.:
P05067, P12023
Gene Symbols:
APP
Immunogen:
Synthetic peptide corresponding to residues 1-16 of beta Amyloid.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
2C8
Conjugate:
Unconjugated
Gene:
APP
Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; be
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11820, 351
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Cytohesin 2
Classification: Monoclonal
Concentration: 2 mg/mL
Formulation: 0.01M PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P63035, Q99418
Gene Symbols: CYTH2
Immunogen: Recombinant, full length human protein.
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: CYT2-21
Conjugate: Unconjugated
Gene: CYTH2
Gene Alias: ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; ARNO; CLM2; CTC-273B12.8; CTS18; CTS18.1; Cyth2; cytohesin 2; cytohesin-2; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2; PSCD2L; Sec7; SEC7 homolog B; Sec7b; SEC7L; Sec7p-L; Sec7p-like
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 116692, 9266
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Cytohesin 2
Classification:
Monoclonal
Concentration:
2 mg/mL
Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P63035, Q99418
Gene Symbols:
CYTH2
Immunogen:
Recombinant, full length human protein.
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
CYT2-21
Conjugate:
Unconjugated
Gene:
CYTH2
Gene Alias:
ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; ARNO; CLM2; CTC-273B12.8; CTS18; CTS18.1; Cyth2; cytohesin 2; cytohesin-2; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2; PSCD2L; Sec7; SEC7 homolog B; Sec7b; SEC7L; Sec7p-L; Sec7p-like
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
116692, 9266
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IRF4
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: Q15306
Gene Symbols: IRF4
Immunogen: Recombinant MUM1 protein.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: MUM1p
Conjugate: Unconjugated
Gene: IRF4
Gene Alias: AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 3662
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
IRF4
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
Q15306
Gene Symbols:
IRF4
Immunogen:
Recombinant MUM1 protein.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
MUM1p
Conjugate:
Unconjugated
Gene:
IRF4
Gene Alias:
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
3662
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: GOSR2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2
Gene Accession No.: O14653, O35165, O35166
Gene Symbols: Gosr2
Immunogen: Recombinant rat membrin with a His6 tag
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Canine, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 4HAD6
Conjugate: Unconjugated
Gene: Gosr2
Gene Alias: 2310032N09Rik; 27 kDa Golgi SNARE protein; Bos1; C76855; EPM6; Golgi SNAP receptor complex member 2; golgi SNARE; Gosr2; Gs27; I79_025823; LOC100766577; Membrin; RP23-272P17.5; SNARE
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100342992, 100519332, 100766577, 56494, 610436, 64154, 9570
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GOSR2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2
Gene Accession No.:
O14653, O35165, O35166
Gene Symbols:
Gosr2
Immunogen:
Recombinant rat membrin with a His6 tag
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Canine, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
4HAD6
Conjugate:
Unconjugated
Gene:
Gosr2
Gene Alias:
2310032N09Rik; 27 kDa Golgi SNARE protein; Bos1; C76855; EPM6; Golgi SNAP receptor complex member 2; golgi SNARE; Gosr2; Gs27; I79_025823; LOC100766577; Membrin; RP23-272P17.5; SNARE
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100342992, 100519332, 100766577, 56494, 610436, 64154, 9570
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid