PIMA126062

SHP-1 Monoclonal Antibody (PTY11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA126062-Each-of-1 In Stock ₹ 45,646.26

PIMA126062 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

SHP-1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

0.01M PBS with no preservative; pH 7.2

Gene Accession No.

P29350

Gene Symbols

PTPN6

Immunogen

Recombinant, full length human protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

PTY11

Conjugate

Unconjugated

Gene

PTPN6

Gene Alias

70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5777

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-26062 detects SHP1 from human samples
  • SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
  • The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
  • SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
  • In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
  • Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
  • Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.

Compare Similar Items

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Img

Thermo Scientific

PIMA126062

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Antigen:
SHP-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.01M PBS with no preservative; pH 7.2

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
Recombinant, full length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
PTY11

Conjugate:
Unconjugated

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA126064

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Antigen:
SAA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P0DJI8

Gene Symbols:
SAA1

Immunogen:
Highly Purified recombinant human SAA (MW: 12kDa)

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Western Blot

Clone:
607

Conjugate:
Unconjugated

Gene:
SAA1

Gene Alias:
amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA126078

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Antigen:
HSC70

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.:
P11142, P19378, P63017, P63018

Gene Symbols:
Hspa8

Immunogen:
Full length, native Hsc70 protein purified from sodium arsenite treated heat-resistant variants of Chinese hamster cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Guinea Pig, Hamster, Human, Multi-species, Mouse, Ovine, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
1B5

Conjugate:
Unconjugated

Gene:
Hspa8

Gene Alias:
2410008N15Rik; AAG2; constitutive heat shock protein 70; constitutively expressed heat shock protein; epididymis luminal protein 33; epididymis secretory sperm binding protein Li 72p; FAM10A1; Heat shock 70 kDa protein 8; heat shock 70kd protein 10; heat shock 70kd protein 10 (HSC71); heat shock 70kD protein 8; heat shock 70kDa protein 8; heat shock cognate; heat shock cognate 70; heat shock cognate 71 kD protein; heat shock cognate 71 kDa protein; heat shock cognate 71 kDa protein-like protein; heat shock cognate 71-kd protein; heat shock cognate hsc73; heat shock cognate protein 54; Heat shock cognate protein 70; heat shock protein 70 cognate; heat shock protein 8; heat shock protein A8; heat shock protein cognate 70; heat shock protein family A (Hsp70) member 8; HEL-33; HEL-S-72p; HIP; HSC54; Hsc70; Hsc70 ATPase; HSC70 protein; Hsc71; Hsc73; HSP70; HSP71; HSP73; Hspa10; Hspa8; hspa8 protein; I79_022974; LAP; LAP1; LAP-1; lipopolysaccharide-associated protein 1; LPS-associated protein 1; MGC131511; MGC29929; NIP71; N-myristoyltransferase inhibitor protein 71; Protein FAM10A1; similar to 7O KDa heat shock cognate protein; SNC6; unnamed protein product; wu:fb01g06; wu:fi48b06

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100348873, 100511890, 100689472, 100713849, 101112844, 15481, 24468, 3312, 479406

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA126098

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Antigen:
G-CSF

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P09919

Gene Symbols:
Csf3

Immunogen:
Purified, recombinant human MBP-GCSFR fusion protein.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Western Blot, Western Blot (Agglutination)

Clone:
S1390

Conjugate:
Unconjugated

Gene:
Csf3

Gene Alias:
C17orf33; colony stimulating factor 3; colony stimulating factor 3 (granulocyte); CSF 3; CSF3; CSF3OS; Csfg; filgrastim; GCSF; G-CSF; Granulocyte colony-stimulating factor; granulocyte-colony stimulating factor; gsf3; lenograstim; MGC45931; MGI-IG; Pluripoietin; RP23-395E10.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1440

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid