PIMA133625
LAIR1 Monoclonal Antibody (NKTA255), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA133625-Each-of-1 | In Stock | ₹ 76,020.06 |
PIMA133625 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 76,020.06
GST (18%): ₹ 13,683.611
Total Price: ₹ 89,703.671
Antigen
LAIR1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q6GTX8
Gene Symbols
LAIR1
Immunogen
NK cells lines B12.100 and AM.25
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
NKTA255
Conjugate
Unconjugated
Gene
LAIR1
Gene Alias
5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3903
Content And Storage
4° C
Form
Liquid
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- LAIR1 (CD305) functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells
- Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11
- It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation
- May also play its inhibitory role independently of SH2-containing phosphatases
- Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta
- Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion
- Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells
- Inhibits the differentiation of peripheral blood precursors towards dendritic cells.
Compare Similar Items
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Antigen: LAIR1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q6GTX8
Gene Symbols: LAIR1
Immunogen: NK cells lines B12.100 and AM.25
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: NKTA255
Conjugate: Unconjugated
Gene: LAIR1
Gene Alias: 5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3903
Content And Storage: 4° C
Form: Liquid
Antigen:
LAIR1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q6GTX8
Gene Symbols:
LAIR1
Immunogen:
NK cells lines B12.100 and AM.25
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
NKTA255
Conjugate:
Unconjugated
Gene:
LAIR1
Gene Alias:
5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3903
Content And Storage:
4° C
Form:
Liquid
Antigen: p21
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide
Gene Accession No.: P38936
Gene Symbols: CDKN1A
Immunogen: Full length native protein (purified) (Human).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: WA-1
Conjugate: Unconjugated
Gene: CDKN1A
Gene Alias: Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1026
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
p21
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide
Gene Accession No.:
P38936
Gene Symbols:
CDKN1A
Immunogen:
Full length native protein (purified) (Human).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
WA-1
Conjugate:
Unconjugated
Gene:
CDKN1A
Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1026
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD19
Classification: Monoclonal
Concentration: 0.17 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P15391
Gene Symbols: Cd19
Immunogen: Hairy Cell Leukemia Cells
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen)
Clone: HD37
Conjugate: Unconjugated
Gene: Cd19
Gene Alias: AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 930
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD19
Classification:
Monoclonal
Concentration:
0.17 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P15391
Gene Symbols:
Cd19
Immunogen:
Hairy Cell Leukemia Cells
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
HD37
Conjugate:
Unconjugated
Gene:
Cd19
Gene Alias:
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
930
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: TGF beta-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P01137, P04202, P17246, P18341, P50414
Gene Symbols: Tgfb1
Immunogen: Human Transforming Growth Factor Beta 1 from platelets
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: TB21
Conjugate: Unconjugated
Gene: Tgfb1
Gene Alias: CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF β; TGF β 1; TGF β1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFβ1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor β1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100008645, 21803, 282089, 443417, 59086, 7040
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TGF beta-1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P01137, P04202, P17246, P18341, P50414
Gene Symbols:
Tgfb1
Immunogen:
Human Transforming Growth Factor Beta 1 from platelets
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
TB21
Conjugate:
Unconjugated
Gene:
Tgfb1
Gene Alias:
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF β; TGF β 1; TGF β1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFβ1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor β1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100008645, 21803, 282089, 443417, 59086, 7040
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid