PIMA170015

CD28 Monoclonal Antibody (JJ319), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA170015-Each-of-1 In Stock ₹ 31,229.40

PIMA170015 - Each of 1

₹ 31,229.40

In Stock

Quantity

1

Base Price: ₹ 31,229.40

GST (18%): ₹ 5,621.292

Total Price: ₹ 36,850.692

Antigen

CD28

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P31042

Gene Symbols

Cd28

Immunogen

Rat CD28 transfected A20J.

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunoprecipitation

Clone

JJ319

Conjugate

Unconjugated

Gene

Cd28

Gene Alias

antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

25660

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein
  • CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes
  • Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells
  • In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death
  • In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28
  • In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR
  • The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells
  • Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary's Disease.

Compare Similar Items

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Img

Thermo Scientific

PIMA170015

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Antigen:
CD28

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P31042

Gene Symbols:
Cd28

Immunogen:
Rat CD28 transfected A20J.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
JJ319

Conjugate:
Unconjugated

Gene:
Cd28

Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25660

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA170020

--


Antigen:
OX40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P15725

Gene Symbols:
Tnfrsf4

Immunogen:
Phytohaemagglutinin-activated rat lymph node cells.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
OX40

Conjugate:
Unconjugated

Gene:
Tnfrsf4

Gene Alias:
ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; Ly-70; lymphoid activation antigene ACT35; MRC OX40; Ox40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4; Tnfrsf4; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1; Txgp1l

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25572

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA170021

--


Antigen:
SIRP alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P97710

Gene Symbols:
SIRPA

Immunogen:
Rat peritoneal macrophages.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Radioimmune Assays (RIA)

Clone:
OX-41

Conjugate:
Unconjugated

Gene:
SIRPA

Gene Alias:
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3;

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25528

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA170025

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Antigen:
CD48

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P10252

Gene Symbols:
Cd48

Immunogen:
Rat T cell blasts (stimulated purified T helper cells with allogeneic irradiated rat spleen cells).

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
MCR OX-45

Conjugate:
Unconjugated

Gene:
Cd48

Gene Alias:
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
245962

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid