PIMA170058

CD59 Monoclonal Antibody (1F5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA170058-Each-of-1 In Stock ₹ 42,480.54

PIMA170058 - Each of 1

₹ 42,480.54

In Stock

Quantity

1

Base Price: ₹ 42,480.54

GST (18%): ₹ 7,646.497

Total Price: ₹ 50,127.037

Antigen

CD59

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O55186, P13987, P58019

Gene Symbols

CD59, Cd59a, Cd59b

Immunogen

Neuraminidase-treated Human Erythrocytes (Neu-HuE)

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry

Clone

1F5

Conjugate

Unconjugated

Gene

CD59

Gene Alias

16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12509, 333883, 966

Content And Storage

4° C

Form

Liquid

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Description

  • MA1-70058 detects CD59 in human samples
  • MA1-70058 has been successfully used in flow cytometry procedures
  • The MA1-70058 immunogen is Neuraminidase-treated Human Erythrocytes (Neu-HuE)
  • Store at 4oC
  • For long term storage, alilquot and freeze unused portion at -20oC in single use volumes
  • Avoid freeze/thaw cycles
  • CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC)
  • CD59 is the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade
  • CD59 also associates with C5b-8 complex and counteracts appropriate formation of cytolytic pore within the plasma membrane
  • Further, CD59 is a low-affinity ligand of human CD2, causes T cell costimulation, and is involved in lymphocyte signal transduction
  • CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
  • Mutations in this gene cause CD59 deficiency, a disease involving hemolytic anemia, thrombosis, and cerebral infarction
  • Multiple alternatively spliced transcript variants of CD59 have been identified.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA170058

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Antigen:
CD59

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O55186, P13987, P58019

Gene Symbols:
CD59, Cd59a, Cd59b

Immunogen:
Neuraminidase-treated Human Erythrocytes (Neu-HuE)

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
1F5

Conjugate:
Unconjugated

Gene:
CD59

Gene Alias:
16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12509, 333883, 966

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA170060

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Antigen:
C5AR1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P21730

Gene Symbols:
C5AR1

Immunogen:
RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
8D6

Conjugate:
Unconjugated

Gene:
C5AR1

Gene Alias:
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
728

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA170062

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Antigen:
CD90

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P01831

Gene Symbols:
Thy1

Immunogen:
CBA/J.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
5a-8

Conjugate:
Unconjugated

Gene:
Thy1

Gene Alias:
CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21838

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA170065

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Antigen:
I-Ab

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P01921, P06342, P06343, P06344, P06345, P06346, P14483

Gene Symbols:
H2-Ab1

Immunogen:
H2-I / Ab.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry

Clone:
28-5-16S

Conjugate:
Unconjugated

Gene:
H2-Ab1

Gene Alias:
Abeta; AI845868; CELIAC1; DADB-249P12.2; H-2 class II histocompatibility antigen, A beta chain; H-2Ab; H2-Ab; H2-Ab1; H2Eb; H-2Eb; H2-iabeta; histocompatibility 2, class II antigen A, beta 1; HLA-DQB; Ia2; Ia-2; Ia4; Ia-4; IAb; I-Abeta; IDDM1; major histocompatibility complex class II beta chain; MGC163794; MGC163796; MHC class II antigen A beta; MHC class II H2-IA-beta-psi; response to metastatic cancers 1; Rmcs1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14961

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid