PIMA180926

CD40 Monoclonal Antibody (LOB7/6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA180926-Each-of-1 In Stock ₹ 49,325.34

PIMA180926 - Each of 1

₹ 49,325.34

In Stock

Quantity

1

Base Price: ₹ 49,325.34

GST (18%): ₹ 8,878.561

Total Price: ₹ 58,203.901

Antigen

CD40

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with <0.1% sodium azide

Gene Accession No.

P25942, Q7YRL5

Gene Symbols

CD40

Immunogen

CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

LOB7/6

Conjugate

Unconjugated

Gene

CD40

Gene Alias

AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

403469, 958

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product requires protein digestion pre-treatment of paraffin sections using trypsin or pronase
  • A suggested positive control for immunohistochemical applications is human tonsil
  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Mouse anti Human CD40 antibody, clone LOB7/6 recognizes the human CD40 cell surface antigen, a 48kDa glycoprotein expressed by B lymphocytes and weakly by some monocytes
  • The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30
  • CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells
  • CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation
  • AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be important for homotypic cell interactions
  • Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction
  • The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis
  • Two alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported
  • Diseases associated with CD40 dysfunction include Type 3 Hyper-Igm immunodeficiency and CD40 ligand deficiency.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA180926

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Antigen:
CD40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with <0.1% sodium azide

Gene Accession No.:
P25942, Q7YRL5

Gene Symbols:
CD40

Immunogen:
CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
LOB7/6

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
403469, 958

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA180944

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Antigen:
CD105

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P17813

Gene Symbols:
ENG

Immunogen:
Cell membrane antigens from fresh leukemia cells.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Equine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
SN6

Conjugate:
PE

Gene:
ENG

Gene Alias:
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100070421, 2022

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Lyophilized

Img

Thermo Scientific

PIMA180984

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Antigen:
CD104

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P16144

Gene Symbols:
ITGB4

Immunogen:
Purified alpha6 beta4 integrin from A431 cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mustelid

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
450-9D

Conjugate:
Unconjugated

Gene:
ITGB4

Gene Alias:
AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3691

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA181040

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Antigen:
GST Tag

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
GST from Schistosoma japonicum.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
vpg66

Conjugate:
Biotin

Gene:
__

Gene Alias:
activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid