PIMA182769

ITGA4 Monoclonal Antibody (PS/2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA182769-Each-of-1 In Stock ₹ 63,442.74

PIMA182769 - Each of 1

₹ 63,442.74

In Stock

Quantity

1

Base Price: ₹ 63,442.74

GST (18%): ₹ 11,419.693

Total Price: ₹ 74,862.433

Antigen

ITGA4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

P13612, Q00651

Gene Symbols

ITGA4

Immunogen

P815 DBA/2 murine mastocytoma cells.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

PS/2

Conjugate

Unconjugated

Gene

ITGA4

Gene Alias

269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

16401, 3676

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This product is a low-endotoxin, preservative-free formulation
  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Rat anti Mouse CD49d monoclonal antibody, clone PS/2 recognizes murine alpha 4 integrin (CD49d), a approximately 150 kDa single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively (Holzmann et al
  • 1989)
  • The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
  • Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
  • Alpha4 chain associates with either beta1 or beta7 chain
  • It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
  • These ligands included Madcam, VCAM, and fibronectin
  • Madcam is known as the principal ligand for integrin alpha4beta7
  • Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA182769

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Antigen:
ITGA4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P13612, Q00651

Gene Symbols:
ITGA4

Immunogen:
P815 DBA/2 murine mastocytoma cells.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
PS/2

Conjugate:
Unconjugated

Gene:
ITGA4

Gene Alias:
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16401, 3676

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIMA182795

--


Antigen:
Dengue Virus Type 1-4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with <0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Proprietary Immunogen.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
Dengue 1-11(3)

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Dengue pan

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA1828

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Antigen:
VRK1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q80X41, Q99986

Gene Symbols:
VRK1

Immunogen:
Recombinant fusion protein GST-VRK1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
1F6

Conjugate:
Unconjugated

Gene:
VRK1

Gene Alias:
51PK; MGC117401; MGC138280; PCH1; PCH1A; Serine/threonine-protein kinase 51PK; serine/threonine-protein kinase VRK1; vaccinia related kinase 1; vaccinia virus B1R-related kinase 1; vaccinia-related kinase 1; VRK1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22367, 7443

Content And Storage:
4° C

Form:
Liquid

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PIMA182815

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Antigen:
C4BPA

Classification:
Monoclonal

Concentration:
1.15 mg/mL

Formulation:
BBS with 0.1% sodium azide; pH 8.4

Gene Accession No.:
P04003

Gene Symbols:
C4BPA

Immunogen:
Native human C4 binding protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Flow Cytometry

Clone:
10-07

Conjugate:
Unconjugated

Gene:
C4BPA

Gene Alias:
AI195242; C4b-binding protein; C4b-binding protein alpha chain; C4bp; C4bpa; complement component 4 binding protein; complement component 4 binding protein alpha; complement component 4 binding protein, alpha; proline-rich protein; PRP; RP11-164O23.4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
722

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid