PIMA191087
Chk1 Monoclonal Antibody (DCS-310), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA191087-Each-of-1 | In Stock | ₹ 51,250.44 |
PIMA191087 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,250.44
GST (18%): ₹ 9,225.079
Total Price: ₹ 60,475.519
Antigen
Chk1
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
O14757, O35280, Q91ZN7
Gene Symbols
Chek1
Immunogen
Recombinant full length protein (Human).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG3
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
DCS-310
Conjugate
Unconjugated
Gene
Chek1
Gene Alias
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1111, 12649, 140583
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Heat in a microwave oven, twice for 10 minutes in citrate buffer, pH 6.5
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Chk1
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: O14757, O35280, Q91ZN7
Gene Symbols: Chek1
Immunogen: Recombinant full length protein (Human).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG3
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: DCS-310
Conjugate: Unconjugated
Gene: Chek1
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1111, 12649, 140583
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Chk1
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O14757, O35280, Q91ZN7
Gene Symbols:
Chek1
Immunogen:
Recombinant full length protein (Human).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG3
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
DCS-310
Conjugate:
Unconjugated
Gene:
Chek1
Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1111, 12649, 140583
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Cytokeratin 5/6
Classification: Monoclonal
Concentration: __
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P02538, P13647
Gene Symbols: KRT5, KRT6A
Immunogen: Cytokeratin 5 (Human).
Quantity: 250 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin)
Clone: D5/16 B4
Conjugate: Unconjugated
Gene: KRT5
Gene Alias: 2310016L08Rik; 3300001P10Rik; 58 kDa cytokeratin; 60-kDa keratin; AW146334; CK5; CK-5; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; Hom s 5; K5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; keratin-5; keratin-6A; Keratin-6-alpha; keratin-6C; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; krt5; KRT5A; Krt6; Krt6a; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; Sak57; similar to keratin complex 2, basic, gene 6a; Tfip8; tuftelin interacting protein 8; type-II keratin Kb12; type-II keratin Kb5; Type-II keratin Kb6
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3852, 3853
Content And Storage: 4° C
Form: Liquid
Antigen:
Cytokeratin 5/6
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P02538, P13647
Gene Symbols:
KRT5, KRT6A
Immunogen:
Cytokeratin 5 (Human).
Quantity:
250 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin)
Clone:
D5/16 B4
Conjugate:
Unconjugated
Gene:
KRT5
Gene Alias:
2310016L08Rik; 3300001P10Rik; 58 kDa cytokeratin; 60-kDa keratin; AW146334; CK5; CK-5; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; Hom s 5; K5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; keratin-5; keratin-6A; Keratin-6-alpha; keratin-6C; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; krt5; KRT5A; Krt6; Krt6a; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; Sak57; similar to keratin complex 2, basic, gene 6a; Tfip8; tuftelin interacting protein 8; type-II keratin Kb12; type-II keratin Kb5; Type-II keratin Kb6
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3852, 3853
Content And Storage:
4° C
Form:
Liquid
Antigen: Cyclosporin A
Classification: Monoclonal
Concentration: 5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: __
Gene Symbols: __
Immunogen: Proprietary immunogen
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Chemical
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: CSZ.22
Conjugate: Unconjugated
Gene: __
Gene Alias: C62H111N11O12; Ciclosporin; Cyclophilin A; Cyclosporin; Cyclosporin A-binding protein; Cyclosporine; Cyclosporine A; CYPA; CYPH; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase A; rotamase A; T cell cyclophilin
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
Cyclosporin A
Classification:
Monoclonal
Concentration:
5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Proprietary immunogen
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Chemical
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
CSZ.22
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
C62H111N11O12; Ciclosporin; Cyclophilin A; Cyclosporin; Cyclosporin A-binding protein; Cyclosporine; Cyclosporine A; CYPA; CYPH; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase A; rotamase A; T cell cyclophilin
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: MCM5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P33992
Gene Symbols: MCM5
Immunogen: Bacterially expressed human Mcm5
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: CRCT5.1 (A2.7A3)
Conjugate: Unconjugated
Gene: MCM5
Gene Alias: AA617332; AI324988; AL033333; Cdc46; CDC46 homolog; DNA replication licensing factor MCM5; MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; Mcmd5; MGC5315; minichromosome maintenance complex component 5; minichromosome maintenance deficient 5 (cell division cycle 46); minichromosome maintenance deficient 5, cell division cycle 46; minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae); P1-CDC46
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4174
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MCM5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P33992
Gene Symbols:
MCM5
Immunogen:
Bacterially expressed human Mcm5
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
CRCT5.1 (A2.7A3)
Conjugate:
Unconjugated
Gene:
MCM5
Gene Alias:
AA617332; AI324988; AL033333; Cdc46; CDC46 homolog; DNA replication licensing factor MCM5; MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; Mcmd5; MGC5315; minichromosome maintenance complex component 5; minichromosome maintenance deficient 5 (cell division cycle 46); minichromosome maintenance deficient 5, cell division cycle 46; minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae); P1-CDC46
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4174
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid