PIMA191618
DFFB Monoclonal Antibody (36A349), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA191618-Each-of-1 | In Stock | ₹ 48,127.50 |
PIMA191618 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,127.50
GST (18%): ₹ 8,662.95
Total Price: ₹ 56,790.45
Antigen
DFFB
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O76075
Gene Symbols
DFFB
Immunogen
Anti-DFF40 monoclonal antibody was raised against a peptide corresponding to amino acids 205 to 222 (SYFDRGAKGGSRLCTPEG) of human DFF40.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
36A349
Conjugate
Unconjugated
Gene
DFFB
Gene Alias
2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; DFFB; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
1677
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA1-91618 detects CAD from human samples
- Caspase-activated DNase (CAD) cleaves chromosomal DNA during apoptosis
- Apoptosis which is a cell death process removing toxic and/or useless cells during mammalian development can be induced by a variety of stimuli, including the death factors of the tumor necrosis factor family, or UV irradiation, anticancer drugs, and survival factor deprivation
- The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units
- CAD, which can be activated by caspases, exists as a complex with its inhibitor, inhibitor of CAD (ICAD)
- ICAD helps correct folding of CAD and remains complexed with CAD to inhibit the DNase activity of CAD
- Caspase, which is activated during the apoptotic process, cleaves ICAD, and the CAD released from ICAD enters the nuclei to cleave the chromosomal DNA
- Internal as well as external signals can activate caspases and this is under the control of the balance between pro-and anti-apoptotic proteins of the Bcl-2 family, heat shock proteins, and inhibitors of apoptosis proteins (IAPs)
- Currently, fourteen members of the caspase family have been identified, of which seven mediate apoptosis.
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Antigen: DFFB
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O76075
Gene Symbols: DFFB
Immunogen: Anti-DFF40 monoclonal antibody was raised against a peptide corresponding to amino acids 205 to 222 (SYFDRGAKGGSRLCTPEG) of human DFF40.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 36A349
Conjugate: Unconjugated
Gene: DFFB
Gene Alias: 2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; DFFB; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 1677
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
DFFB
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O76075
Gene Symbols:
DFFB
Immunogen:
Anti-DFF40 monoclonal antibody was raised against a peptide corresponding to amino acids 205 to 222 (SYFDRGAKGGSRLCTPEG) of human DFF40.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
36A349
Conjugate:
Unconjugated
Gene:
DFFB
Gene Alias:
2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; DFFB; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
1677
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NOP58
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 10mM sodium azide
Gene Accession No.: A6ZPE5
Gene Symbols: NOP58
Immunogen: This was raised against a yeast nucleolar prep, and screened by immunocytochemistry and western blotting.
Quantity: 250 μL
Primary or Secondary: Primary
Target Species: Yeast
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 34B12
Conjugate: Unconjugated
Gene: NOP58
Gene Alias: HSPC120; MSSP; Nap65; Nol5; NOP5; NOP5/NOP58; Nop58; NOP58 ribonucleoprotein; NOP58 ribonucleoprotein homolog; Nopp140 associated protein; nopp140-associated protein of 65 kDa; Nucleolar protein 5; nucleolar protein 58; nucleolar protein NOP5/NOP58; nucleolar protein NOP58; O6108; RNA-processing protein NOP58; SIK; SIK similar protein; SIK-similar protein; YOR310C
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 854487
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NOP58
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 10mM sodium azide
Gene Accession No.:
A6ZPE5
Gene Symbols:
NOP58
Immunogen:
This was raised against a yeast nucleolar prep, and screened by immunocytochemistry and western blotting.
Quantity:
250 μL
Primary or Secondary:
Primary
Target Species:
Yeast
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
34B12
Conjugate:
Unconjugated
Gene:
NOP58
Gene Alias:
HSPC120; MSSP; Nap65; Nol5; NOP5; NOP5/NOP58; Nop58; NOP58 ribonucleoprotein; NOP58 ribonucleoprotein homolog; Nopp140 associated protein; nopp140-associated protein of 65 kDa; Nucleolar protein 5; nucleolar protein 58; nucleolar protein NOP5/NOP58; nucleolar protein NOP58; O6108; RNA-processing protein NOP58; SIK; SIK similar protein; SIK-similar protein; YOR310C
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
854487
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: HSPA9
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2
Gene Accession No.: O35501, P38646, P38647, P48721, P99502, Q3ZCH0
Gene Symbols: HSPA9, hspa9.S
Immunogen: Grp75 isolated from human Molt4 cells.
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Bovine, Canine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat, X. laevis
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 30A5
Conjugate: Unconjugated
Gene: HSPA9
Gene Alias: 70 kDa heat shock protein; 74kDa; 75 kDa glucose-regulated protein; C3H-specific antigen; catecholamine-regulated protein 40; CRP40; CSA; epididymis secretory sperm binding protein Li 124m; EVPLS; GRP 75; GRP75; GRP-75; heat shock 70 kDa protein 9; heat shock 70 kDa protein 9B; heat shock 70kD protein 9B; heat shock 70kDa protein 9 (mortalin); heat shock 70kDa protein 9A; heat shock 70kDa protein 9B (mortalin-2); Heat shock protein; heat shock protein 9; heat shock protein 9A; heat shock protein cognate 74; heat shock protein family A (Hsp70) member 9; heat shock protein family A (Hsp70) member 9 S homeolog; heat shock protein, 74 kDa, A; heat shock protein, A; HEL-S-124m; Hsc74; HSP; Hsp74; Hsp74a; hspa9; hspa9.S; Hspa9a; hspa9-a; hspa9b; hspa9-b; hypothetical protein; I79_009139; MGC4500; mortalin; mortalin, perinuclear; mortalin2; mortalin-2; mot; MOT2; Mot-2; Mthsp70; mt-HSP70; MTHSP75; p66 MOT; p66-mortalin; pbp74; Peptide-binding protein 74; RCJMB04_2m8; SAAN; SIDBA4; stress-70 protein mitochondrial-like protein; stress-70 protein, mitochondrial; Stress-70 protein, mitochondrial-like protein; XELAEV_18020021mg
Host Species: Mouse
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 100347135, 100521183, 100689405, 100719079, 101112054, 15526, 291671, 3313, 379314, 474697, 517535
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
HSPA9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2
Gene Accession No.:
O35501, P38646, P38647, P48721, P99502, Q3ZCH0
Gene Symbols:
HSPA9, hspa9.S
Immunogen:
Grp75 isolated from human Molt4 cells.
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat, X. laevis
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
30A5
Conjugate:
Unconjugated
Gene:
HSPA9
Gene Alias:
70 kDa heat shock protein; 74kDa; 75 kDa glucose-regulated protein; C3H-specific antigen; catecholamine-regulated protein 40; CRP40; CSA; epididymis secretory sperm binding protein Li 124m; EVPLS; GRP 75; GRP75; GRP-75; heat shock 70 kDa protein 9; heat shock 70 kDa protein 9B; heat shock 70kD protein 9B; heat shock 70kDa protein 9 (mortalin); heat shock 70kDa protein 9A; heat shock 70kDa protein 9B (mortalin-2); Heat shock protein; heat shock protein 9; heat shock protein 9A; heat shock protein cognate 74; heat shock protein family A (Hsp70) member 9; heat shock protein family A (Hsp70) member 9 S homeolog; heat shock protein, 74 kDa, A; heat shock protein, A; HEL-S-124m; Hsc74; HSP; Hsp74; Hsp74a; hspa9; hspa9.S; Hspa9a; hspa9-a; hspa9b; hspa9-b; hypothetical protein; I79_009139; MGC4500; mortalin; mortalin, perinuclear; mortalin2; mortalin-2; mot; MOT2; Mot-2; Mthsp70; mt-HSP70; MTHSP75; p66 MOT; p66-mortalin; pbp74; Peptide-binding protein 74; RCJMB04_2m8; SAAN; SIDBA4; stress-70 protein mitochondrial-like protein; stress-70 protein, mitochondrial; Stress-70 protein, mitochondrial-like protein; XELAEV_18020021mg
Host Species:
Mouse
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
100347135, 100521183, 100689405, 100719079, 101112054, 15526, 291671, 3313, 379314, 474697, 517535
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TCP1
Classification: Monoclonal
Concentration: __
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P11983, P18279, P28480, Q32L40
Gene Symbols: TCP1
Immunogen: Purified recombinant mouse TCP1 alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp 1b gene expressed in E. coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Hamster, Mouse, Ovine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG2c
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 23c
Conjugate: Unconjugated
Gene: TCP1
Gene Alias: 65 kDa antigen; AI528772; c-cpn; CCT; Cct1; Ccta; CCTalpha; CCT-alpha; chaperonin-containing T-complex alpha subunit TCP1; chaperonin-containing T-complex polypeptide alpha subunit; cytosolic chaperonin containing t-complex polypeptide 1; D6S230E; hypothetical protein; p63; tailless complex polypeptide 1; tailless complex polypeptide 1A; Tailless complex polypeptide 1B; t-complex 1; t-complex polypeptide 1; t-complex protein 1; T-complex protein 1 alpha subunit-like protein; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; T-complex protein 1, alpha subunit; Tcp1; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp63; TRic; Unknown (protein for MGC:133746); YD8142.13; YD8142B.04; YDR212W
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100135437, 100302435, 100689476, 21454, 24818, 484064, 512043
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TCP1
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P11983, P18279, P28480, Q32L40
Gene Symbols:
TCP1
Immunogen:
Purified recombinant mouse TCP1 alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp 1b gene expressed in E. coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Hamster, Mouse, Ovine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG2c
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
23c
Conjugate:
Unconjugated
Gene:
TCP1
Gene Alias:
65 kDa antigen; AI528772; c-cpn; CCT; Cct1; Ccta; CCTalpha; CCT-alpha; chaperonin-containing T-complex alpha subunit TCP1; chaperonin-containing T-complex polypeptide alpha subunit; cytosolic chaperonin containing t-complex polypeptide 1; D6S230E; hypothetical protein; p63; tailless complex polypeptide 1; tailless complex polypeptide 1A; Tailless complex polypeptide 1B; t-complex 1; t-complex polypeptide 1; t-complex protein 1; T-complex protein 1 alpha subunit-like protein; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; T-complex protein 1, alpha subunit; Tcp1; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp63; TRic; Unknown (protein for MGC:133746); YD8142.13; YD8142B.04; YDR212W
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100135437, 100302435, 100689476, 21454, 24818, 484064, 512043
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid