PIMA32520AY
NPM1 Monoclonal Antibody (FC-61991), Alexa Fluor™ 647, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA32520AY-Each-of-1 | In Stock | ₹ 38,758.68 |
PIMA32520AY - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
NPM1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.
P06748, P13084, Q61937
Gene Symbols
NPM1
Immunogen
NPM/B23 purified from rat hepatoma
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
FC-61991
Conjugate
Alexa Fluor 647
Gene
NPM1
Gene Alias
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18148, 25498, 4869
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
Compare Similar Items
Show Difference
Antigen: NPM1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06748, P13084, Q61937
Gene Symbols: NPM1
Immunogen: NPM/B23 purified from rat hepatoma
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: FC-61991
Conjugate: Alexa Fluor 647
Gene: NPM1
Gene Alias: B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
NPM1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P06748, P13084, Q61937
Gene Symbols:
NPM1
Immunogen:
NPM/B23 purified from rat hepatoma
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
FC-61991
Conjugate:
Alexa Fluor 647
Gene:
NPM1
Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: NPM1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06748, P13084, Q61937
Gene Symbols: NPM1
Immunogen: NPM/B23 purified from rat hepatoma
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry
Clone: FC-61991
Conjugate: Alexa Fluor 555
Gene: NPM1
Gene Alias: B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
NPM1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P06748, P13084, Q61937
Gene Symbols:
NPM1
Immunogen:
NPM/B23 purified from rat hepatoma
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry
Clone:
FC-61991
Conjugate:
Alexa Fluor 555
Gene:
NPM1
Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: NPM1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06748, P13084, Q61937
Gene Symbols: NPM1
Immunogen: NPM/B23 purified from rat hepatoma
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry
Clone: FC-61991
Conjugate: Alexa Fluor 488
Gene: NPM1
Gene Alias: B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
NPM1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P06748, P13084, Q61937
Gene Symbols:
NPM1
Immunogen:
NPM/B23 purified from rat hepatoma
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry
Clone:
FC-61991
Conjugate:
Alexa Fluor 488
Gene:
NPM1
Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Lamin B2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P14732, P21619, Q03252
Gene Symbols: LMNB2
Immunogen: Extracts from chicken nuclei
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Chicken, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry
Clone: E-3
Conjugate: Alexa Fluor 647
Gene: LMNB2
Gene Alias: EPM9; fc15d06; im:7142331; LAMB2; lamin; lamin A/C; lamin B2; lamin B2 S homeolog; lamin B3; lamin-B2; Lamin-L(II); LMN2; LMNA; lmnb2; lmnb2.S; lmnb2-a; lmnb2-b; MGC2721; RGD1563803; unnamed protein product; wu:fb94e05; wu:fb95e12; wu:fc15d06; wu:fc49h03; XELAEV_18009631mg
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16907, 299625, 396222, 84823
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Lamin B2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P14732, P21619, Q03252
Gene Symbols:
LMNB2
Immunogen:
Extracts from chicken nuclei
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Chicken, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry
Clone:
E-3
Conjugate:
Alexa Fluor 647
Gene:
LMNB2
Gene Alias:
EPM9; fc15d06; im:7142331; LAMB2; lamin; lamin A/C; lamin B2; lamin B2 S homeolog; lamin B3; lamin-B2; Lamin-L(II); LMN2; LMNA; lmnb2; lmnb2.S; lmnb2-a; lmnb2-b; MGC2721; RGD1563803; unnamed protein product; wu:fb94e05; wu:fb95e12; wu:fc15d06; wu:fc49h03; XELAEV_18009631mg
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16907, 299625, 396222, 84823
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid