PIMA3965555
FAK Monoclonal Antibody (ZF002), Alexa Fluor™ 555, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA3965555-Each-of-1 | In Stock | ₹ 37,988.64 |
PIMA3965555 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,988.64
GST (18%): ₹ 6,837.955
Total Price: ₹ 44,826.595
Antigen
FAK
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene Accession No.
O35346, P34152, Q05397
Gene Symbols
PTK2
Immunogen
Recombinant protein derived from the N-terminal region of the mouse and rat FAK-1 proteins
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunocytochemistry
Clone
ZF002
Conjugate
Alexa Fluor 555
Gene
PTK2
Gene Alias
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14083, 25614, 5747
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
- FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
- Tyrosine 397 is the autophosphorylation site of FAK, and involved in its initial activation
- This phosphorylated site binds Src family SH2 domains and the p85 subunit of PI3-Kinase, and activates cell migration and invasion
- Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
- FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
- FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
- Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
- Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
- In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
- In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
- Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.
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Antigen: FAK
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O35346, P34152, Q05397
Gene Symbols: PTK2
Immunogen: Recombinant protein derived from the N-terminal region of the mouse and rat FAK-1 proteins
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry
Clone: ZF002
Conjugate: Alexa Fluor 555
Gene: PTK2
Gene Alias: CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14083, 25614, 5747
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
FAK
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
O35346, P34152, Q05397
Gene Symbols:
PTK2
Immunogen:
Recombinant protein derived from the N-terminal region of the mouse and rat FAK-1 proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry
Clone:
ZF002
Conjugate:
Alexa Fluor 555
Gene:
PTK2
Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14083, 25614, 5747
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: FAK
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O35346, P34152, Q05397
Gene Symbols: PTK2
Immunogen: Recombinant protein derived from the N-terminal region of the mouse and rat FAK-1 proteins
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry
Clone: ZF002
Conjugate: Alexa Fluor 647
Gene: PTK2
Gene Alias: CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14083, 25614, 5747
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
FAK
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
O35346, P34152, Q05397
Gene Symbols:
PTK2
Immunogen:
Recombinant protein derived from the N-terminal region of the mouse and rat FAK-1 proteins
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry
Clone:
ZF002
Conjugate:
Alexa Fluor 647
Gene:
PTK2
Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14083, 25614, 5747
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: GST Tag
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Recombinant purified full-length GST
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Tag
Product Type: Antibody
Isotype: IgG1
Applications: Immunoprecipitation, Western Blot
Clone: 8-326
Conjugate: Unconjugated
Gene: __
Gene Alias: activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Antigen:
GST Tag
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Recombinant purified full-length GST
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Tag
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunoprecipitation, Western Blot
Clone:
8-326
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Antigen: GST Tag
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: MES with proprietary stabilizer and no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Recombinant purified full-length GST
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: __
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 8-326
Conjugate: DyLight 800 4X PEG
Gene: __
Gene Alias: activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
GST Tag
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
MES with proprietary stabilizer and no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Recombinant purified full-length GST
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
__
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
8-326
Conjugate:
DyLight 800 4X PEG
Gene:
__
Gene Alias:
activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, do not freeze
Form:
Liquid