PIMA512490

CD45RA Monoclonal Antibody (4KB5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA512490-Each-of-1 In Stock ₹ 40,213.20

PIMA512490 - Each of 1

₹ 40,213.20

In Stock

Quantity

1

Base Price: ₹ 40,213.20

GST (18%): ₹ 7,238.376

Total Price: ₹ 47,451.576

Antigen

CD45RA

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

Hairy cell leukemia cells

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

4KB5

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-12490 targets CD45RA in IHC (P) applications and shows reactivity with Human samples
  • The MA5-12490 immunogen is hairy cell leukemia cells
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing and these isoforms differ in their extracellular domains, however, they share identical transmembrane and cytoplasmic domains
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
  • CD45 is expressed on cells of the human hematopoietic lineage, with the exception of mature red cells and is not detected on differentiated cells of other tissues
  • It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions
  • Diseases associated with CD45 dysfunction include severe combined immunodeficiency and Hepatitis C.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA512490

--


Antigen:
CD45RA

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Hairy cell leukemia cells

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4KB5

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C

Form:
Liquid

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Thermo Scientific

PIMA512502

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Antigen:
BrdU

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
BrdU conjugated to BSA

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
BU20A

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
5-Bromo-2-deoxyuridine; Bromodeoxyuridine

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

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Thermo Scientific

PIMA512508

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Antigen:
NPM1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P06748, Q61937

Gene Symbols:
NPM1

Immunogen:
GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 aa of ALK protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
NA24

Conjugate:
Unconjugated

Gene:
NPM1

Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18148, 4869

Content And Storage:
4° C

Form:
Liquid

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PIMA512526

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Antigen:
CD1a

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P06126

Gene Symbols:
Cd1, CD1A

Immunogen:
Human thymus cells

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
O10

Conjugate:
Unconjugated

Gene:
CD1A

Gene Alias:
CD1; CD1 antigen; CD1.1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cd1a1; CD1A1 antigen; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
111334, 909

Content And Storage:
4° C

Form:
Liquid