MA5-13398 targets Thrombospondin in FACS, ICC/IF, IHC (P), IM, IP, and WB applications and shows reactivity with Bovine, Canine, Equine, Human, mouse, Ovine, Porcine, and Rat samples
The MA5-13398 immunogen is reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets
Thrombospondin is a protein from platelet a-granules
It is made up of three identical subunits bound by interchain disulfides
It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.