PIPA5114443

SMURF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114443-Each-of-1 In Stock ₹ 44,705.10

PIPA5114443 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SMURF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Smurf1

Gene Alias

4930431E10Rik; E3 ubiquitin ligase SMURF1; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF1; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF1; HECT-type E3 ubiquitin transferase SMURF2; hSMURF1; hSMURF2; KIAA1625; mKIAA1625; RGD1309707; SMAD specific E3 ubiquitin protein ligase 1; SMAD specific E3 ubiquitin protein ligase 2; Smad ubiquitination regulatory factor 1; SMAD ubiquitination regulatory factor 2; Smad-specific E3 ubiquitin ligase 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF1; SMURF2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57154, 690516

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

Q9HCE7

Gene Symbols

Smurf1

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human SMURF1 (326-351aa DHNNRTTQFTDPRLHHIMNHQCQLKE).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Members of the transforming growth factor-beta (TGFB) family signal through type I and type II serine/threonine-kinase receptors, which in turn activate the SMAD signaling pathway
  • Bone morphogenetic protein (BMP) receptors target SMAD1, SMAD5, and SMAD8, whereas receptors for activin and TGFB (e
  • g., ACVR1 and TGFBR1, respectively) target SMAD2 and SMAD3
  • Phosphorylation of these receptor-regulated SMADs induces their association with the common-partner SMAD, SMAD4
  • Smurf1, a HECT domain E3 ubiquitin ligase, regulates cell polarity and protrusive activity and is required to maintain the transformed morphology and motility of a tumor cell
  • Atypical protein kinase C-zeta (PKC2), an effector of the Cdc42/Rac1-PAR6 polarity complex, recruits Smurf1 to cellular protrusions, where it controlled the local level of RhoA
  • Smurf1 thus links the polarity complex to degradation of RhoA in lamellipodia and filopodia to prevent RhoA signaling during dynamic membrane movements.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5114443

--


Antigen:
SMURF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smurf1

Gene Alias:
4930431E10Rik; E3 ubiquitin ligase SMURF1; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF1; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF1; HECT-type E3 ubiquitin transferase SMURF2; hSMURF1; hSMURF2; KIAA1625; mKIAA1625; RGD1309707; SMAD specific E3 ubiquitin protein ligase 1; SMAD specific E3 ubiquitin protein ligase 2; Smad ubiquitination regulatory factor 1; SMAD ubiquitination regulatory factor 2; Smad-specific E3 ubiquitin ligase 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF1; SMURF2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57154, 690516

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q9HCE7

Gene Symbols:
Smurf1

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human SMURF1 (326-351aa DHNNRTTQFTDPRLHHIMNHQCQLKE).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114444

--


Antigen:
IFN gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25712

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 0.05MG sodium azide

Gene Accession No.:
P01581

Gene Symbols:
IFNG

Immunogen:
E. coli-derived rat IFN gamma recombinant protein (Position: 23-156).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114445

--


Antigen:
IFN gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3458

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 0.05MG sodium azide

Gene Accession No.:
P01579

Gene Symbols:
IFNG

Immunogen:
E. coli-derived human IFN gamma recombinant protein (Position: Q24-Q166).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114446

--


Antigen:
SARS-CoV-2 Spike Protein S1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of SARS-CoV-2 (COVID-19) spike (S1). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG