PIMA532768

STING Recombinant Rabbit Monoclonal Antibody (JM03-47), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532768-Each-of-1 In Stock ₹ 44,619.54

PIMA532768 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

STING

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q86WV6

Gene Symbols

TMEM173

Immunogen

Recombinant protein within Human TMEM173 aa 220-379

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot, Immunofluorescence, Western Blot

Clone

JM03-47

Conjugate

Unconjugated

Gene

TMEM173

Gene Alias

2610307O08Rik, endoplasmic reticulum IFN stimulator, endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, hypothetical LOC533661, mediator of IRF3 activation, Mita, mitochondrial mediator of IRF3 activation, mitochondrial transmembrane protein 173, MMITA, Mpys, mSTING, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, poSTING, RGD1562552, rSTING, SAVI, Stimulator of interferon genes protein, stimulator of interferon response cGAMP interactor 1, STING, STING1, tm173, Tmem173, Transmembrane protein 173

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

340061

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling
  • This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression
  • STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway
  • Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532768

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Antigen:
STING

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q86WV6

Gene Symbols:
TMEM173

Immunogen:
Recombinant protein within Human TMEM173 aa 220-379

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot, Immunofluorescence, Western Blot

Clone:
JM03-47

Conjugate:
Unconjugated

Gene:
TMEM173

Gene Alias:
2610307O08Rik, endoplasmic reticulum IFN stimulator, endoplasmic reticulum interferon stimulator, ERIS, hMITA, hSTING, hypothetical LOC533661, mediator of IRF3 activation, Mita, mitochondrial mediator of IRF3 activation, mitochondrial transmembrane protein 173, MMITA, Mpys, mSTING, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, poSTING, RGD1562552, rSTING, SAVI, Stimulator of interferon genes protein, stimulator of interferon response cGAMP interactor 1, STING, STING1, tm173, Tmem173, Transmembrane protein 173

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
340061

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532771

--


Antigen:
TXNIP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q5M7W1, Q8BG60, Q9H3M7

Gene Symbols:
TXNIP

Immunogen:
Synthetic peptide within Human TXNIP aa 50-99

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM60-35

Conjugate:
Unconjugated

Gene:
TXNIP

Gene Alias:
1200008J08Rik, AA682105, ARRDC6, EST01027, HHCPA78, hyperlipidemia 1, Hyplip1, Tbp-2, THIF, thioredoxin binding protein 2, thioredoxin binding protein-2, thioredoxin interacting protein, thioredoxin-binding protein 2, Thioredoxin-interacting protein, TXNIP, upregulated by 1,25-dihydroxyvitamin D-3, VDUP1, Vitamin D3 up-regulated protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10628, 117514, 56338

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532772

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Antigen:
UBA2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9UBT2, Q9Z1F9

Gene Symbols:
UBA2

Immunogen:
Synthetic peptide within Human SAE2/UBA2 aa 39-88

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
JM66-53

Conjugate:
Unconjugated

Gene:
UBA2

Gene Alias:
AA986091, Anthracycline-associated resistance ARX, Arx, EGK_10449, FLJ13058, HRIHFB2115, SAE2, SUMO1 activating enzyme subunit 2, Sumo-1 activating enzyme subunit 2, SUMO-activating enzyme subunit 2, UBA1, UBA2, UBA2, ubiquitin-activating enzyme E1 homolog, ubiquitin like modifier activating enzyme 2, ubiquitin-like 1 (sentrin) activating enzyme E1B, ubiquitin-like 1 (sentrin) activating enzyme subunit 2, ubiquitin-like 1-activating enzyme E1B, ubiquitin-like modifier activating enzyme 2, ubiquitin-like modifier-activating enzyme 2, Ubl1a2, Uble1b

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10054, 308508, 50995

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532773

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Antigen:
Alix

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q8WUM4, Q9QZA2, Q9WU78

Gene Symbols:
Pdcd6ip

Immunogen:
Recombinant protein within Human ALIX aa 1-160

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JM85-31

Conjugate:
Unconjugated

Gene:
Pdcd6ip

Gene Alias:
AI480591, AIP1, ALG-2 interacting protein 1, ALG-2 interacting protein X, ALG-2-interacting protein 1, Alg2-interacting protein 1, ALG-2-interacting protein X, Alg2-interacting protein X, Alix, apoptosis-linked gene 2-interacting protein X, AW544830, C76364, dopamine receptor interacting protein 4, DRIP4, E2F1-inducible protein, Eig2, Hp95, KIAA1375, MGC17003, mKIAA1375, PDCD6-interacting protein, Pdcd6ip, pdcd6ip.L, programmed cell death 6 interacting protein, programmed cell death 6 interacting protein L homeolog, programmed cell death 6-interacting protein, putative signal tranduction protein Xp95, RGD1561176, Signal transduction protein Xp95, XELAEV_18031317mg, xp95

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10015, 18571, 501083

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid