PIMA513590

MMP2 Monoclonal Antibody (CA-4001 (CA719E3C)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA513590-Each-of-1 In Stock ₹ 48,726.42

PIMA513590 - Each of 1

₹ 48,726.42

In Stock

Quantity

1

Base Price: ₹ 48,726.42

GST (18%): ₹ 8,770.756

Total Price: ₹ 57,497.176

Antigen

MMP2

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P08253, P33434, P33436

Gene Symbols

MMP2

Immunogen

N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot

Clone

CA-4001 (CA719E3C)

Conjugate

Unconjugated

Gene

MMP2

Gene Alias

72 kDa gelatinase; 72 kDa type IV collagenase; 72 kDa type IV collagenase isoform a preproprotein; 72kD gelatinase; 72kD type IV collagenase; 72kDa gelatinase; 72kDa type IV collagenase; CLG 4A; CLG4; CLG4A; Collagenase; collagenase type IV-A; endopeptidase; GelA; gelatinase A; Gelatinase alpha; Mat; matrix metallo protease; matrix metallopeptidase 2; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); matrix metalloprotease 2; matrix metalloproteinase; matrix metalloproteinase 2; matrix metalloproteinase 2 (72 KDa type IV collagenase); matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); matrix metalloproteinase-2; matrix metalloproteinase-II; MMP; MMP2; MMP-2; MMP-2 protein; MMP-II; MMPs; MONA; neutrophil gelatinase; PEX; prepro-72kDa matrix metalloproteinase; Progelatinase A; TBE1; TBE-1; wu:fa99h12; wu:fk89d01

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

17390, 4313, 81686

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-13590 targets MMP-2 (72kDa Collagenase IV) in IA and WB applications and shows reactivity with Human, mouse, and Rat samples
  • The MA5-13590 immunogen is n-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
  • MMP (matrix metalloproteinase) are proteolytic enzymes capable of degrading connective tissue components
  • MMP have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs)
  • MMPa and TIMPs play a significant role in regulating angiogenesis
  • MMP2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids, and contains the basic structure of propeptide, catalytic, and hemopexin domains
  • The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane-bound zincendopeptidases
  • Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non-fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins
  • In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc-binding site characterizes the structure of the MMPs
  • Functionally, MMP2 is involved in tissue remodeling
  • Mutations in MMP-2 gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome
  • Two transcript variants encoding different isoforms of MMP-2 have been found.

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Show Difference

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Thermo Scientific

PIMA513590

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Antigen:
MMP2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P08253, P33434, P33436

Gene Symbols:
MMP2

Immunogen:
N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot

Clone:
CA-4001 (CA719E3C)

Conjugate:
Unconjugated

Gene:
MMP2

Gene Alias:
72 kDa gelatinase; 72 kDa type IV collagenase; 72 kDa type IV collagenase isoform a preproprotein; 72kD gelatinase; 72kD type IV collagenase; 72kDa gelatinase; 72kDa type IV collagenase; CLG 4A; CLG4; CLG4A; Collagenase; collagenase type IV-A; endopeptidase; GelA; gelatinase A; Gelatinase alpha; Mat; matrix metallo protease; matrix metallopeptidase 2; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); matrix metalloprotease 2; matrix metalloproteinase; matrix metalloproteinase 2; matrix metalloproteinase 2 (72 KDa type IV collagenase); matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); matrix metalloproteinase-2; matrix metalloproteinase-II; MMP; MMP2; MMP-2; MMP-2 protein; MMP-II; MMPs; MONA; neutrophil gelatinase; PEX; prepro-72kDa matrix metalloproteinase; Progelatinase A; TBE1; TBE-1; wu:fa99h12; wu:fk89d01

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17390, 4313, 81686

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA513616

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Antigen:
POLE

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q07864, Q9WVF7

Gene Symbols:
POLE

Immunogen:
Purified recombinant human DNA polymerase epsilon corresponding to aa1-176

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunoprecipitation, Western Blot

Clone:
93H3A

Conjugate:
Unconjugated

Gene:
POLE

Gene Alias:
CRCS12; DNA polymerase epsilon catalytic subunit A; DNA polymerase epsilon catalytic subunit protein; DNA polymerase epsilon, catalytic subunit; DNA polymerase II subunit A; DNA-directed DNA polymerase epsilon; FILS; Pole; POLE1; pol-epsilon; polymerase (DNA directed), epsilon; polymerase (DNA directed), epsilon, catalytic subunit; polymerase (DNA) epsilon, catalytic subunit

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18973, 5426, 785457

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA513631

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Antigen:
CBP

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P45481, Q6JHU9, Q92793

Gene Symbols:
CREBBP

Immunogen:
E1A affinity purified p300 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mink, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
NM11

Conjugate:
Biotin

Gene:
CREBBP

Gene Alias:
AW558298; CBP; CBP/p300; CREB binding protein; CREB-binding protein; CREBBP; KAT3A; p300/CBP; RSTS; RTS

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12914, 1387, 54244

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA513634

--


Antigen:
CBP

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P45481, Q6JHU9, Q92793

Gene Symbols:
CREBBP

Immunogen:
E1A affinity purified p300 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mink, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
NM11

Conjugate:
Unconjugated

Gene:
CREBBP

Gene Alias:
AW558298; CBP; CBP/p300; CREB binding protein; CREB-binding protein; CREBBP; KAT3A; p300/CBP; RSTS; RTS

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12914, 1387, 54244

Content And Storage:
4° C

Form:
Liquid