PIMA513773

INSR alpha Monoclonal Antibody (47-9), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA513773-Each-of-1 In Stock ₹ 46,245.18

PIMA513773 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

INSR alpha

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P06213

Gene Symbols

INSR

Immunogen

IM-9 lymphocytes followed by purified insulin receptor

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Bovine, Human, Ovine, Porcine

Product Type

Antibody

Isotype

IgG1

Applications

Inhibition Assays

Clone

47-9

Conjugate

Unconjugated

Gene

INSR

Gene Alias

4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3643, 396755, 408017, 443431

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-13773 targets Insulin Receptor alpha in IA applications and shows reactivity with Bovine, Human, Ovine, and Porcine samples
  • The MA5-13773 immunogen is iM-9 lymphocytes followed by purified insulin receptor
  • Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
  • The insulin receptor
  • Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
  • These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
  • Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
  • Both these signaling cascades are also important for the development of cancer.

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Thermo Scientific

PIMA513773

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Antigen:
INSR alpha

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
IM-9 lymphocytes followed by purified insulin receptor

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Ovine, Porcine

Product Type:
Antibody

Isotype:
IgG1

Applications:
Inhibition Assays

Clone:
47-9

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3643, 396755, 408017, 443431

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA513783

--


Antigen:
INSR

Classification:
Monoclonal

Concentration:
50 μg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P06213, P15208

Gene Symbols:
INSR

Immunogen:
Recombinant-fragment including the C-terminal 100 amino acids of human insulin receptor

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
__

Isotype:
IgG1

Applications:
Affinity Purification, ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
CT-3

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16337, 3643

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA513794

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Antigen:
Cdc25A

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P30304, P48964, P48965

Gene Symbols:
CDC25A

Immunogen:
Purified recombinant CDC25A

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
DCS-120

Conjugate:
Unconjugated

Gene:
CDC25A

Gene Alias:
CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12530, 171102, 993

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA513799

--


Antigen:
IGF1R alpha

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P08069

Gene Symbols:
Igf1r

Immunogen:
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
24-31

Conjugate:
Biotin

Gene:
Igf1r

Gene Alias:
A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
4° C

Form:
Liquid