PIMA513994

Bax Monoclonal Antibody (2D2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA513994-Each-of-1 In Stock ₹ 47,956.38

PIMA513994 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

Bax

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

Q07812

Gene Symbols

BAX

Immunogen

A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. This amino acid sequence is NOT shared by mouse and rat bax protein.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

2D2

Conjugate

Unconjugated

Gene

BAX

Gene Alias

apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

581

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-13994 targets Bax in IF, IHC (P), and WB applications and shows reactivity with Human samples
  • The MA5-13994 immunogen is a synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein
  • This amino acid sequence is NOT shared by mouse and rat bax protein
  • BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis
  • Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function
  • Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2
  • The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain
  • Bcl-2 is also expressed in different Isoforms
  • Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha
  • Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa)
  • BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis
  • Overexpression of BAX functions to promote cell death
  • BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.

Compare Similar Items

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Img

Thermo Scientific

PIMA513994

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Antigen:
Bax

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q07812

Gene Symbols:
BAX

Immunogen:
A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. This amino acid sequence is NOT shared by mouse and rat bax protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2D2

Conjugate:
Unconjugated

Gene:
BAX

Gene Alias:
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
581

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514003

--


Antigen:
Bax

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q07812, Q07813, Q63690

Gene Symbols:
BAX

Immunogen:
A Synthetic peptide, aa 12-24 (Cys-GPTSSEQIMKTGA), of human Bax protein. This amino acid sequence is shared by human, mouse and rat Bax protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
6A7

Conjugate:
Unconjugated

Gene:
BAX

Gene Alias:
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12028, 24887, 581

Content And Storage:
4° C

Form:
Liquid

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Thermo Scientific

PIMA514017

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Antigen:
Melan-A

Classification:
Cocktail

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q16655

Gene Symbols:
MLANA

Immunogen:
Recombinant hMART-1 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
M2-7C10, M2-9E3

Conjugate:
Unconjugated

Gene:
MLANA

Gene Alias:
A930034P04Rik; Antigen LB39-AA; antigen SK29-AA; MART1; MART-1; melan-A; melanoma antigen recognized by T-cells 1; melanoma associated antigen recognized by T-cells 1; MLANA; Protein Melan-A

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2315

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514077

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Antigen:
MUC1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P15941, Q02496

Gene Symbols:
MUC1

Immunogen:
Delipidated extract of human milk fat globule membranes

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
E29

Conjugate:
Unconjugated

Gene:
MUC1

Gene Alias:
ADMCKD; ADMCKD1; Breast carcinoma-associated antigen DF3; CA 15-3; Cancer antigen 15-3; carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; J19; KL-6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease, autosomal dominant; Muc1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin1; mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen; Tumor-associated mucin

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17829, 4582

Content And Storage:
4° C

Form:
Liquid