PIMA514505

Progesterone Receptor Monoclonal Antibody (SP2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514505-Each-of-1 In Stock ₹ 89,410.20

PIMA514505 - Each of 1

₹ 89,410.20

In Stock

Quantity

1

Base Price: ₹ 89,410.20

GST (18%): ₹ 16,093.836

Total Price: ₹ 1,05,504.036

Antigen

Progesterone Receptor

Classification

Monoclonal

Concentration

0.08 mg/mL

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.

P06401

Gene Symbols

PGR

Immunogen

Recombinant protein encoding human progesterone receptor 412-526 aa

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

SP2

Conjugate

Unconjugated

Gene

PGR

Gene Alias

9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • MA5-14505 targets Progesterone Receptor in IHC (P) and WB applications and shows reactivity with Human samples
  • MA5-14505 has been successfully used in western blotting, immunofluorescence, and immunohistochemistry analysis of Progesterone Receptor in human and mouse samples
  • The MA5-14505 immunogen is recombinant protein encoding human progesterone receptor 412-526 aa
  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

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Img

Thermo Scientific

PIMA514505

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Antigen:
Progesterone Receptor

Classification:
Monoclonal

Concentration:
0.08 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP2

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA514509

--


Antigen:
ErbB2 (HER-2)

Classification:
Recombinant Monoclonal

Concentration:
0.122 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P04626

Gene Symbols:
ERBB2

Immunogen:
Recombinant protein encoding extracellular domain of human HER-2

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP3

Conjugate:
Unconjugated

Gene:
ERBB2

Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2064

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA514512

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Antigen:
Cyclin D1

Classification:
Recombinant Monoclonal

Concentration:
0.045 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P24385, P25322, P39948

Gene Symbols:
CCND1

Immunogen:
A synthetic peptide from C-terminus of human cyclin D1

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP4

Conjugate:
Unconjugated

Gene:
CCND1

Gene Alias:
AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12443, 58919, 595

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA514520

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Antigen:
Ki-67

Classification:
Monoclonal

Concentration:
0.031 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
E9PVX6, P46013

Gene Symbols:
Mki67

Immunogen:
Synthetic peptide within Human Ki67 aa 1200-1300

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP6

Conjugate:
Unconjugated

Gene:
Mki67

Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17345, 291234, 4288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid