PIMA514568
COX2 Monoclonal Antibody (SP21), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514568-Each-of-1 | In Stock | ₹ 51,421.56 |
PIMA514568 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,421.56
GST (18%): ₹ 9,255.881
Total Price: ₹ 60,677.441
Antigen
COX2
Classification
Monoclonal
Concentration
0.006 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.
P35354
Gene Symbols
PTGS2
Immunogen
A synthetic peptide from C-terminus of rat cox2
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
SP21
Conjugate
Unconjugated
Gene
PTGS2
Gene Alias
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5743
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA5-14568 targets COX2 in IHC (P) applications and shows reactivity with Human samples
- The MA5-14568 immunogen is a synthetic peptide from C-terminus of rat cox2
- COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
- The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
- It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
- Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
- In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
- COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
- Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
- COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.
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Antigen: COX2
Classification: Monoclonal
Concentration: 0.006 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: P35354
Gene Symbols: PTGS2
Immunogen: A synthetic peptide from C-terminus of rat cox2
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP21
Conjugate: Unconjugated
Gene: PTGS2
Gene Alias: COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5743
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
COX2
Classification:
Monoclonal
Concentration:
0.006 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
P35354
Gene Symbols:
PTGS2
Immunogen:
A synthetic peptide from C-terminus of rat cox2
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP21
Conjugate:
Unconjugated
Gene:
PTGS2
Gene Alias:
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5743
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: AMACR
Classification: Monoclonal
Concentration: __
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q9UHK6
Gene Symbols: AMACR
Immunogen: Human p504s/AMACR polypeptide
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 13H4
Conjugate: Unconjugated
Gene: AMACR
Gene Alias: 2-arylpropionyl-CoA epimerase; 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; alpha-methylacyl-Coenzyme A racemase; Amacr; AMACRD; amcr; CBAS4; Da1-8; Macr1; Marc1; OTTHUMP00000219978; OTTHUMP00000219979; RACE; RM
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 23600
Content And Storage: 4° C
Form: Liquid
Antigen:
AMACR
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q9UHK6
Gene Symbols:
AMACR
Immunogen:
Human p504s/AMACR polypeptide
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
13H4
Conjugate:
Unconjugated
Gene:
AMACR
Gene Alias:
2-arylpropionyl-CoA epimerase; 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; alpha-methylacyl-Coenzyme A racemase; Amacr; AMACRD; amcr; CBAS4; Da1-8; Macr1; Marc1; OTTHUMP00000219978; OTTHUMP00000219979; RACE; RM
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
23600
Content And Storage:
4° C
Form:
Liquid
Antigen: PSMA
Classification: Recombinant Monoclonal
Concentration: 0.113 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: Q04609
Gene Symbols: FOLH1
Immunogen: C-terminal of Prostate Specific Membrane Antigen
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: SP29
Conjugate: Unconjugated
Gene: FOLH1
Gene Alias: Cell growth-inhibiting gene 27 protein; FGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1; FOLH; Folh1; Folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; GIG27; glutamate carboxylase II; glutamate carboxypeptidase 2; Glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; mopsm; Naalad; NAALAD1; NAALAdase; NAALADase I; N-acetylated alpha-linked acidic dipeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; prostate specific membrane antigen; prostate specific membrane antigen variant F; prostate-specific membrane antigen; Prostate-specific membrane antigen homolog; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2346
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PSMA
Classification:
Recombinant Monoclonal
Concentration:
0.113 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
Q04609
Gene Symbols:
FOLH1
Immunogen:
C-terminal of Prostate Specific Membrane Antigen
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
SP29
Conjugate:
Unconjugated
Gene:
FOLH1
Gene Alias:
Cell growth-inhibiting gene 27 protein; FGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1; FOLH; Folh1; Folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; GIG27; glutamate carboxylase II; glutamate carboxypeptidase 2; Glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; mopsm; Naalad; NAALAD1; NAALAdase; NAALADase I; N-acetylated alpha-linked acidic dipeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; prostate specific membrane antigen; prostate specific membrane antigen variant F; prostate-specific membrane antigen; Prostate-specific membrane antigen homolog; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2346
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: DOG-1
Classification: Recombinant Monoclonal
Concentration: 0.057 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: Q5XXA6
Gene Symbols: ANO1
Immunogen: Synthetic peptide of human Dog1
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP31
Conjugate: Unconjugated
Gene: ANO1
Gene Alias: ANO1; anoctamin 1; anoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; FLJ10261; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV2; TAOS2; Tmem16a; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 55107
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DOG-1
Classification:
Recombinant Monoclonal
Concentration:
0.057 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
Q5XXA6
Gene Symbols:
ANO1
Immunogen:
Synthetic peptide of human Dog1
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP31
Conjugate:
Unconjugated
Gene:
ANO1
Gene Alias:
ANO1; anoctamin 1; anoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; FLJ10261; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV2; TAOS2; Tmem16a; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
55107
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid