PIMA514874
PKC lambda/iota Monoclonal Antibody (F.699.5), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514874-Each-of-1 | In Stock | ₹ 51,079.32 |
PIMA514874 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,079.32
GST (18%): ₹ 9,194.278
Total Price: ₹ 60,273.598
Antigen
PKC lambda/iota
Classification
Monoclonal
Concentration
20 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
F1M7Y5, P41743, Q62074
Gene Symbols
PRKCI
Immunogen
Synthetic peptide corresponding to human PKC lambda/iota
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
F.699.5
Conjugate
Unconjugated
Gene
PRKCI
Gene Alias
2310021H13Rik; AI427505; aPKClambda; aPKC-lambda/iota; atypical protein kinase C-lambda/iota; DXS1179E; hypothetical protein; mKIAA4165; nPKC-iota; Pkci; Pkcl; PKClambda; PRKCI; Prkcl; PRKC-lambda/iota; protein kinase C iota; protein kinase C iota type; protein kinase C, iota; protein kinase C, lambda
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18759, 5584, 84006
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with other PKC isoforms
- The PKC family of serine/threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways
- In humans, at least 12 different PKC polypeptides have been identified
- These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
- PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
- The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes
- This protein kinase is calcium-independent and phospholipid-dependent
- It is not activated by phorbolesters or diacylglycerol
- This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway
- This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis
- There is a single exon pseudogene mapped on chromosome X.
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Antigen: PKC lambda/iota
Classification: Monoclonal
Concentration: 20 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: F1M7Y5, P41743, Q62074
Gene Symbols: PRKCI
Immunogen: Synthetic peptide corresponding to human PKC lambda/iota
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: F.699.5
Conjugate: Unconjugated
Gene: PRKCI
Gene Alias: 2310021H13Rik; AI427505; aPKClambda; aPKC-lambda/iota; atypical protein kinase C-lambda/iota; DXS1179E; hypothetical protein; mKIAA4165; nPKC-iota; Pkci; Pkcl; PKClambda; PRKCI; Prkcl; PRKC-lambda/iota; protein kinase C iota; protein kinase C iota type; protein kinase C, iota; protein kinase C, lambda
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18759, 5584, 84006
Content And Storage: -20°C
Form: Liquid
Antigen:
PKC lambda/iota
Classification:
Monoclonal
Concentration:
20 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
F1M7Y5, P41743, Q62074
Gene Symbols:
PRKCI
Immunogen:
Synthetic peptide corresponding to human PKC lambda/iota
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
F.699.5
Conjugate:
Unconjugated
Gene:
PRKCI
Gene Alias:
2310021H13Rik; AI427505; aPKClambda; aPKC-lambda/iota; atypical protein kinase C-lambda/iota; DXS1179E; hypothetical protein; mKIAA4165; nPKC-iota; Pkci; Pkcl; PKClambda; PRKCI; Prkcl; PRKC-lambda/iota; protein kinase C iota; protein kinase C iota type; protein kinase C, iota; protein kinase C, lambda
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18759, 5584, 84006
Content And Storage:
-20°C
Form:
Liquid
Antigen: SUMO1
Classification: Monoclonal
Concentration: 23 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P63165, P63166, Q5I0H3
Gene Symbols: SUMO1
Immunogen: Synthetic peptide from the amino terminus of human SUMO-1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: T.243.0
Conjugate: Unconjugated
Gene: SUMO1
Gene Alias: CG4494-PA; DAP1; GAP modifying protein 1; GAP-modifying protein 1; GMP1; LD07775p; OFC10; OK/SW-cl.43; OTTHUMP00000202403; OTTHUMP00000202404; OTTHUMP00000202405; OTTHUMP00000202406; OTTHUMP00000202409; OTTHUMP00000202410; PIC1; SENP2; sentrin; Sentrin-1; small ubiquitin-like modifier 1; small ubiquitin-related modifier 1; small ubiquitin-related modifier-1; SMT3; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 1 (yeast); Smt3C; Smt3h3; SMTP3; Sumo1; SUMO-1; SUMO-1 related peptidase; Ubiquitin-homology domain protein PIC1; ubiquitin-like 1; ubiquitin-like 1 (sentrin); ubiquitin-like protein SMT3C; Ubiquitin-like protein UBL1; UBL1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22218, 301442, 7341
Content And Storage: -20°C
Form: Liquid
Antigen:
SUMO1
Classification:
Monoclonal
Concentration:
23 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P63165, P63166, Q5I0H3
Gene Symbols:
SUMO1
Immunogen:
Synthetic peptide from the amino terminus of human SUMO-1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
T.243.0
Conjugate:
Unconjugated
Gene:
SUMO1
Gene Alias:
CG4494-PA; DAP1; GAP modifying protein 1; GAP-modifying protein 1; GMP1; LD07775p; OFC10; OK/SW-cl.43; OTTHUMP00000202403; OTTHUMP00000202404; OTTHUMP00000202405; OTTHUMP00000202406; OTTHUMP00000202409; OTTHUMP00000202410; PIC1; SENP2; sentrin; Sentrin-1; small ubiquitin-like modifier 1; small ubiquitin-related modifier 1; small ubiquitin-related modifier-1; SMT3; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 1 (yeast); Smt3C; Smt3h3; SMTP3; Sumo1; SUMO-1; SUMO-1 related peptidase; Ubiquitin-homology domain protein PIC1; ubiquitin-like 1; ubiquitin-like 1 (sentrin); ubiquitin-like protein SMT3C; Ubiquitin-like protein UBL1; UBL1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22218, 301442, 7341
Content And Storage:
-20°C
Form:
Liquid
Antigen: Bcl-10
Classification: Monoclonal
Concentration: 32 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: O95999, Q9QYN5, Q9Z0H7
Gene Symbols: BCL10
Immunogen: Synthetic peptide corresponding to residues surrounding Ser60 of Bcl10
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: E.177.7
Conjugate: Unconjugated
Gene: BCL10
Gene Alias: AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12042, 83477, 8915
Content And Storage: -20°C
Form: Liquid
Antigen:
Bcl-10
Classification:
Monoclonal
Concentration:
32 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
O95999, Q9QYN5, Q9Z0H7
Gene Symbols:
BCL10
Immunogen:
Synthetic peptide corresponding to residues surrounding Ser60 of Bcl10
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
E.177.7
Conjugate:
Unconjugated
Gene:
BCL10
Gene Alias:
AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12042, 83477, 8915
Content And Storage:
-20°C
Form:
Liquid
Antigen: EHMT2
Classification: Monoclonal
Concentration: 21 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: Q96KQ7, Q9Z148
Gene Symbols: Ehmt2
Immunogen: Synthetic peptide corresponding to the carboxy terminus of the human G9a/EHMT2 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: B.133.9
Conjugate: Unconjugated
Gene: Ehmt2
Gene Alias: ankyrin repeat-containing protein; Bat8; C6orf30; D17Ertd710e; DKFZp686H08213; Ehmt2; euchromatic histone lysine methyltransferase 2; euchromatic histone lysine N-methyltransferase 2; euchromatic histone-lysine N-methyltransferase 2; FLJ35547; G9a; G9A histone methyltransferase; GAT8; H3 ly; H3-K9-Histone-Methyl-Transferase; H3-K9-HMTase 3; histone H3-K9 methyltransferase 3; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; HLA-B associated transcript 8; HLA-B associated transcript 8, rat orthologue; HLA-B-associated transcript 8; KMT1C; lysine N-methyltransferase 1C; NG36; NG36/G9a; Protein G9a
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10919, 110147, 361798
Content And Storage: -20°C
Form: Liquid
Antigen:
EHMT2
Classification:
Monoclonal
Concentration:
21 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
Q96KQ7, Q9Z148
Gene Symbols:
Ehmt2
Immunogen:
Synthetic peptide corresponding to the carboxy terminus of the human G9a/EHMT2 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
B.133.9
Conjugate:
Unconjugated
Gene:
Ehmt2
Gene Alias:
ankyrin repeat-containing protein; Bat8; C6orf30; D17Ertd710e; DKFZp686H08213; Ehmt2; euchromatic histone lysine methyltransferase 2; euchromatic histone lysine N-methyltransferase 2; euchromatic histone-lysine N-methyltransferase 2; FLJ35547; G9a; G9A histone methyltransferase; GAT8; H3 ly; H3-K9-Histone-Methyl-Transferase; H3-K9-HMTase 3; histone H3-K9 methyltransferase 3; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; HLA-B associated transcript 8; HLA-B associated transcript 8, rat orthologue; HLA-B-associated transcript 8; KMT1C; lysine N-methyltransferase 1C; NG36; NG36/G9a; Protein G9a
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10919, 110147, 361798
Content And Storage:
-20°C
Form:
Liquid