PIMA514882

FAS Monoclonal Antibody (H.831.6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514882-Each-of-1 In Stock ₹ 45,646.26

PIMA514882 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

FAS

Classification

Monoclonal

Concentration

206 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P25445, Q63199

Gene Symbols

FAS

Immunogen

Synthetic peptide corresponding to residues surrounding Lys259 of human Fas, within the intracellular region

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

H.831.6

Conjugate

Unconjugated

Gene

FAS

Gene Alias

AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

246097, 355

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • FAS (Fas, CD95, APO-1) is a 46 kDa transmembrane glycoprotein that functions as a cell death receptor of the TNFR (tumor necrosis factor receptor) superfamily
  • FAS also exists in a soluble form that weight approximately 26kDa
  • Stimulation of FAS results in aggregation of its intracellular FAS-associated death domains (FADD), formation of the death-inducing signaling complex (DISC) and activation of caspases
  • The auto-proteolytic processing of the caspases in the complex trigger a downstream cascade that leads to apoptosis
  • FAS has been shown to activate NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and is involved in transducing the proliferating signals in normal diploid fibroblast and T cells
  • At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described
  • The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full-length isoform
  • The Fas/Fas ligand system has been shown to play a role in a number of human diseases such as AIDS, hepatitis and cancer
  • It is also assumed that induction of apoptosis through FAS ligand pathway is predominantly involved in anti-viral immune responses.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA514882

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Antigen:
FAS

Classification:
Monoclonal

Concentration:
206 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P25445, Q63199

Gene Symbols:
FAS

Immunogen:
Synthetic peptide corresponding to residues surrounding Lys259 of human Fas, within the intracellular region

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
H.831.6

Conjugate:
Unconjugated

Gene:
FAS

Gene Alias:
AI196731; ALPS1A; APO1; APO-1; Apo1 antigen; Apo-1 antigen; APO-1 cell surface antigen; Apo-1 Fas; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; FAS; Fas (TNF receptor superfamily member 6); Fas (TNF receptor superfamily member); Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; Fas antigen (ATP1); Fas cell surface death receptor; Fas receptor; FAS1; FASLG receptor; FASTM; lpr; lymphoproliferation; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; TNF receptor superfamily member 6; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 26; Tumor necrosis factor receptor superfamily, member 6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
246097, 355

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514884

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Antigen:
GCN5

Classification:
Monoclonal

Concentration:
134 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q92830, Q9JHD2

Gene Symbols:
KAT2A

Immunogen:
Synthetic peptide corresponding to the amino terminus of human GCN5L2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
S.775.4

Conjugate:
Unconjugated

Gene:
KAT2A

Gene Alias:
1110051E14Rik; AAS104; ADA4; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; Gcn5l2; general control of amino acid synthesis 5-like 2; general control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2; Kat2a; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97; SWI9; YGR252W

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14534, 2648, 303539

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514885

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Antigen:
SCD

Classification:
Monoclonal

Concentration:
6 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P13516

Gene Symbols:
Scd1

Immunogen:
Synthetic peptide corresponding to residues surrounding Leu35 of mouse SCD1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
G.545.10

Conjugate:
Unconjugated

Gene:
Scd1

Gene Alias:
AA589638; ab; acyl-CoA desaturase; Acyl-CoA desaturase 1; acyl-CoA desaturase 2; AI265570; asebia; delta(9)-desaturase; Delta(9)-desaturase 1; delta(9)-desaturase 2; Delta-9 desaturase; delta-9 desaturase 1; Delta-9 desaturase 2; delta-9-desaturase; FADS5; fatty acid desaturase; Fatty acid desaturase 1; fatty acid desaturase 2; HGNC:10571; hSCD1; MSTP008; OTTHUMP00000020280; predicted protein of HQ0998; PRO0998; PRO1933; Scd; Scd1; Scd-1; Scd2; SCDOS; stearoyl-CoA desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase 1; Stearoyl-CoA desaturase 2; stearoyl-CoA desaturase opposite strand; stearoyl-Coenzyme A desaturase 1; stearoyl-Coenzyme A desaturase 2; stearyl-CoA desaturase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20249

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514886

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Antigen:
Radixin

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P26043, P35241

Gene Symbols:
Rdx

Immunogen:
Synthetic peptide corresponding to residues near the carboxy terminus of human radixin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
K.353.0

Conjugate:
Unconjugated

Gene:
Rdx

Gene Alias:
AA516625; DFNB24; ESP10; radixin; radixin isoform; Rdx

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19684, 315655, 5962

Content And Storage:
-20°C

Form:
Liquid