PIMA514941

Thioredoxin 1 Monoclonal Antibody (H.753.8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514941-Each-of-1 In Stock ₹ 46,159.62

PIMA514941 - Each of 1

₹ 46,159.62

In Stock

Quantity

1

Base Price: ₹ 46,159.62

GST (18%): ₹ 8,308.732

Total Price: ₹ 54,468.352

Antigen

Thioredoxin 1

Classification

Monoclonal

Concentration

18 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P10599, P10639, P11232

Gene Symbols

TXN, Txn1

Immunogen

Synthetic peptide corresponding to residues surrounding Ala9 of human thioredoxin 1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

H.753.8

Conjugate

Unconjugated

Gene

TXN

Gene Alias

ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116484, 22166, 7295

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells
  • Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site
  • The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds
  • Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor
  • The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations
  • Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53, NF-kB and AP-1 (T1-151)
  • Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

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Img

Thermo Scientific

PIMA514941

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Antigen:
Thioredoxin 1

Classification:
Monoclonal

Concentration:
18 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P10599, P10639, P11232

Gene Symbols:
TXN, Txn1

Immunogen:
Synthetic peptide corresponding to residues surrounding Ala9 of human thioredoxin 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
H.753.8

Conjugate:
Unconjugated

Gene:
TXN

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116484, 22166, 7295

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514942

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Antigen:
LKB1

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q15831

Gene Symbols:
STK11

Immunogen:
Synthetic peptide corresponding to the sequence of human LKB1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
B.593.0

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6794

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514943

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Antigen:
Phospho-JNK1/JNK2 (Thr183, Tyr185)

Classification:
Monoclonal

Concentration:
293 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6

Gene Symbols:
MAPK8, MAPK9

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr183/Tyr185 of human SAPK/JNK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Drosophila, Human, Mouse, Rat, Yeast

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
F.971.6

Conjugate:
Unconjugated

Gene:
MAPK8

Gene Alias:
AI849689; AI851083; C-jun kinase; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 8; MAP kinase 9; MAPK; MAPK 8; MAPK 9; Mapk8; Mapk9; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; OTTHUMP00000019552; p54 gamma; p54a; p54-alpha; p54aSAPK; Phospho-JNK; PRKM; PRKM8; Prkm9; protein kinase JNK1; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPK; SAPK 1; SAPK gamma; SAPK1; SAPK1A; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1c; stress-activated protein kinase JNK1; Stress-activated protein kinase JNK2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 26419, 26420, 50658, 5599, 5601

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514945

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Antigen:
AMPK beta-1

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P80387, Q9R078, Q9Y478

Gene Symbols:
PRKAB1

Immunogen:
Synthetic peptide corresponding to residues surrounding Val176 of human AMPKβ1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
H.743.5

Conjugate:
Unconjugated

Gene:
PRKAB1

Gene Alias:
1300015D22Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase, beta subunit; AAKB1; AMP-activated protein kinase beta subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta-1 chain; AMPK subunit beta-1; AMPKb; AMPK-beta1; AU021155; E430008F22; HAMPKb; kinase AMPK-beta1; kinase pAMPK; pAMPK; Prkab1; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100156537, 100755226, 19079, 5564

Content And Storage:
-20°C

Form:
Liquid