PIMA514949
p21 Monoclonal Antibody (R.229.6), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514949-Each-of-1 | In Stock | ₹ 51,421.56 |
PIMA514949 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,421.56
GST (18%): ₹ 9,255.881
Total Price: ₹ 60,677.441
Antigen
p21
Classification
Monoclonal
Concentration
244 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P38936
Gene Symbols
CDKN1A
Immunogen
Synthetic peptide corresponding to residues near the carboxy-terminus of human p21
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
R.229.6
Conjugate
Unconjugated
Gene
CDKN1A
Gene Alias
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1026
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit
- This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays
- It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications
- Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with other CDK inhibitors
- Protein p21 is a tumor suppressor protein which is an inhibitor of Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53
- P21 is important in the response of cells to genotoxic stress and a major transcriptional target of p53 protein
- The occurrence of p21 in the nucleus executes binding and inhibition activity of cyclin dependent kinases Cdk1 and Cdk2, and blocks the transition from G1 phase into S phase or from G2 phase into mitosis after DNA damage, which enables the repair of damaged DNA
- In the cytoplasm, p21 protein has an anti-apoptotic effect
- P21 is able to bind to and inhibit caspase 3, as well as the apoptotic kinases ASK1 and JNK
- P21 exhibits a dual function in carcinogenesis, and acts as a tumor suppressor, prevents apoptosis, and acts as an oncogene.
Compare Similar Items
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Antigen: p21
Classification: Monoclonal
Concentration: 244 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P38936
Gene Symbols: CDKN1A
Immunogen: Synthetic peptide corresponding to residues near the carboxy-terminus of human p21
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: R.229.6
Conjugate: Unconjugated
Gene: CDKN1A
Gene Alias: Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1026
Content And Storage: -20°C
Form: Liquid
Antigen:
p21
Classification:
Monoclonal
Concentration:
244 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P38936
Gene Symbols:
CDKN1A
Immunogen:
Synthetic peptide corresponding to residues near the carboxy-terminus of human p21
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
R.229.6
Conjugate:
Unconjugated
Gene:
CDKN1A
Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1026
Content And Storage:
-20°C
Form:
Liquid
Antigen: p38 MAPK beta
Classification: Monoclonal
Concentration: 114 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: Q15759
Gene Symbols: MAPK11
Immunogen: Synthetic peptide corresponding to residues around the carboxy terminus of p38β MAPK
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: F.10.8
Conjugate: Unconjugated
Gene: MAPK11
Gene Alias: MAP kinase 11; MAP kinase p38 beta; MAPK 11; Mapk11; mitogen activated protein kinase 11; mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; OTTHUMP00000196655; p38-2; P38b; p38beta; P38BETA2; Prkm11; protein kinase, mitogen activated kinase, 11, p38beta; SAPK2; SAPK2b; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5600
Content And Storage: -20°C
Form: Liquid
Antigen:
p38 MAPK beta
Classification:
Monoclonal
Concentration:
114 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
Q15759
Gene Symbols:
MAPK11
Immunogen:
Synthetic peptide corresponding to residues around the carboxy terminus of p38β MAPK
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
F.10.8
Conjugate:
Unconjugated
Gene:
MAPK11
Gene Alias:
MAP kinase 11; MAP kinase p38 beta; MAPK 11; Mapk11; mitogen activated protein kinase 11; mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; OTTHUMP00000196655; p38-2; P38b; p38beta; P38BETA2; Prkm11; protein kinase, mitogen activated kinase, 11, p38beta; SAPK2; SAPK2b; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5600
Content And Storage:
-20°C
Form:
Liquid
Antigen: SUMO2/SUMO3
Classification: Monoclonal
Concentration: 25 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P55854, P61956, P61957, P61959, Q5XIF4, Q9Z172
Gene Symbols: SUMO2, Sumo3
Immunogen: Synthetic peptide from the amino terminus of human SUMO-3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: J.778.2
Conjugate: Unconjugated
Gene: SUMO2
Gene Alias: 2810014B19Rik; D10Ertd345e; GMP1; HSMT3; I79_000932; MIF2 suppressor; Sentrin; sentrin 2; sentrin-2; small ubiquitin-like modifier 2; small ubiquitin-like modifier 3; small ubiquitin-like modifier 3 L homeolog; small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; Smt3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2 (yeast); SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 3 (yeast); SMT3 supressor of mif two 3 homolog 2; SMT3A; Smt3B; SMT3C; SMT3H1; SMT3H2; SMT3H3; SUMO-1; SUMO2; SUMO-2; Sumo3; SUMO-3; sumo3.L; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; UBL1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 170930, 20610, 499417, 6612, 6613, 690244
Content And Storage: -20°C
Form: Liquid
Antigen:
SUMO2/SUMO3
Classification:
Monoclonal
Concentration:
25 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P55854, P61956, P61957, P61959, Q5XIF4, Q9Z172
Gene Symbols:
SUMO2, Sumo3
Immunogen:
Synthetic peptide from the amino terminus of human SUMO-3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
J.778.2
Conjugate:
Unconjugated
Gene:
SUMO2
Gene Alias:
2810014B19Rik; D10Ertd345e; GMP1; HSMT3; I79_000932; MIF2 suppressor; Sentrin; sentrin 2; sentrin-2; small ubiquitin-like modifier 2; small ubiquitin-like modifier 3; small ubiquitin-like modifier 3 L homeolog; small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; Smt3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2 (yeast); SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 3 (yeast); SMT3 supressor of mif two 3 homolog 2; SMT3A; Smt3B; SMT3C; SMT3H1; SMT3H2; SMT3H3; SUMO-1; SUMO2; SUMO-2; Sumo3; SUMO-3; sumo3.L; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; UBL1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
170930, 20610, 499417, 6612, 6613, 690244
Content And Storage:
-20°C
Form:
Liquid
Antigen: PPP2R1A
Classification: Monoclonal
Concentration: 11 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P30153, Q76MZ3
Gene Symbols: PPP2R1A
Immunogen: Synthetic peptide corresponding to the sequence of human PP2A A Subunit protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: J.613.4
Conjugate: Unconjugated
Gene: PPP2R1A
Gene Alias: 29B; 6330556D22Rik; 65 kDa regulatory subunit of protein phosphatase; A/PR65; alpha isoform of regulatory subunit A, protein phosphatase 2; CG13383; CG17291; CG17291-PA; CG17291-PB; CG17291-PC; CG17291-PD; CG17291-PE; CG33297; Dmel\CG17291; Dmel_CG17291; dPP2A A; DPR65; Medium tumor antigen-associated 61 kDa protein; MGC786; MRD36; PP2A; PP2A 29B; PP2A 65kD subunit A; PP2A A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2A[A]; Pp2A29B; PP2A-29B; Pp2A-29B-PA; Pp2A-29B-PB; Pp2A-29B-PC; Pp2A-29B-PD; Pp2A-29B-PE; PP2A-A; PP2AAALPHA; PP2A-Aalpha; PP2Ac; PP2CA; PP2Calpha; Ppp2r1a; PR65; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2 scaffold subunit Aalpha; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2A; protein phosphatase 2A at 29B; protein phosphatase PP2A; Protein phosphatase PP2A regulatory subunit A; protein phosphate 2A; regulatory subunit A of type 2A protein phosphatase; RP-C; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; serine/threonine protein phosphatase A subunit type 2A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; testicular secretory protein Li 1; Unknown (protein for MGC:128399)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 117281, 51792, 5518
Content And Storage: -20°C
Form: Liquid
Antigen:
PPP2R1A
Classification:
Monoclonal
Concentration:
11 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P30153, Q76MZ3
Gene Symbols:
PPP2R1A
Immunogen:
Synthetic peptide corresponding to the sequence of human PP2A A Subunit protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
J.613.4
Conjugate:
Unconjugated
Gene:
PPP2R1A
Gene Alias:
29B; 6330556D22Rik; 65 kDa regulatory subunit of protein phosphatase; A/PR65; alpha isoform of regulatory subunit A, protein phosphatase 2; CG13383; CG17291; CG17291-PA; CG17291-PB; CG17291-PC; CG17291-PD; CG17291-PE; CG33297; Dmel\CG17291; Dmel_CG17291; dPP2A A; DPR65; Medium tumor antigen-associated 61 kDa protein; MGC786; MRD36; PP2A; PP2A 29B; PP2A 65kD subunit A; PP2A A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2A[A]; Pp2A29B; PP2A-29B; Pp2A-29B-PA; Pp2A-29B-PB; Pp2A-29B-PC; Pp2A-29B-PD; Pp2A-29B-PE; PP2A-A; PP2AAALPHA; PP2A-Aalpha; PP2Ac; PP2CA; PP2Calpha; Ppp2r1a; PR65; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2 scaffold subunit Aalpha; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2A; protein phosphatase 2A at 29B; protein phosphatase PP2A; Protein phosphatase PP2A regulatory subunit A; protein phosphate 2A; regulatory subunit A of type 2A protein phosphatase; RP-C; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; serine/threonine protein phosphatase A subunit type 2A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; testicular secretory protein Li 1; Unknown (protein for MGC:128399)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
117281, 51792, 5518
Content And Storage:
-20°C
Form:
Liquid